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1
Fbxo45-mediated degradation of the tumor-suppressor Par-4 regulates cancer cell survival.
Cell Death Differ. 2014 Oct;21(10):1535-45. doi: 10.1038/cdd.2014.92. Epub 2014 Jul 4.
2
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73.
Oncogene. 2009 Sep 3;28(35):3157-66. doi: 10.1038/onc.2009.177. Epub 2009 Jul 6.
5
CRL3IBTK Regulates the Tumor Suppressor Pdcd4 through Ubiquitylation Coupled to Proteasomal Degradation.
J Biol Chem. 2015 May 29;290(22):13958-71. doi: 10.1074/jbc.M114.634535. Epub 2015 Apr 16.
6
Fbxo45 inhibits calcium-sensitive proteolysis of N-cadherin and promotes neuronal differentiation.
J Biol Chem. 2014 Oct 10;289(41):28448-59. doi: 10.1074/jbc.M114.561241. Epub 2014 Aug 20.
7
Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage.
Proc Natl Acad Sci U S A. 2011 Aug 23;108(34):14103-8. doi: 10.1073/pnas.1108799108. Epub 2011 Aug 8.
8
The E3 ubiquitin ligase SCF(Fbxo7) mediates proteasomal degradation of UXT isoform 2 (UXT-V2) to inhibit the NF-κB signaling pathway.
Biochim Biophys Acta Gen Subj. 2021 Jan;1865(1):129754. doi: 10.1016/j.bbagen.2020.129754. Epub 2020 Sep 30.
10
Fbxo45 facilitates pancreatic carcinoma progression by targeting USP49 for ubiquitination and degradation.
Cell Death Dis. 2022 Mar 12;13(3):231. doi: 10.1038/s41419-022-04675-2.

引用本文的文献

1
FBXO45 restricts HIV-1 replication by inducing SQSTM1/p62-mediated autophagic degradation of Tat.
J Virol. 2025 Mar 18;99(3):e0191224. doi: 10.1128/jvi.01912-24. Epub 2025 Feb 12.
2
The FBXO45-GEF-H1 Axis Controls Germinal Center Formation and B-cell Lymphomagenesis.
Cancer Discov. 2025 Apr 2;15(4):838-861. doi: 10.1158/2159-8290.CD-24-0442.

本文引用的文献

1
Par-4 downregulation promotes breast cancer recurrence by preventing multinucleation following targeted therapy.
Cancer Cell. 2013 Jul 8;24(1):30-44. doi: 10.1016/j.ccr.2013.05.007. Epub 2013 Jun 13.
2
Prostate apoptosis response 4 (Par-4), a novel substrate of caspase-3 during apoptosis activation.
Mol Cell Biol. 2012 Feb;32(4):826-39. doi: 10.1128/MCB.06321-11. Epub 2011 Dec 19.
3
βTrCP regulates BMI1 protein turnover via ubiquitination and degradation.
Cell Cycle. 2011 Apr 15;10(8):1322-30. doi: 10.4161/cc.10.8.15372.
4
Sensitivity to antitubulin chemotherapeutics is regulated by MCL1 and FBW7.
Nature. 2011 Mar 3;471(7336):110-4. doi: 10.1038/nature09779.
5
Structural basis for Par-4 recognition by the SPRY domain- and SOCS box-containing proteins SPSB1, SPSB2, and SPSB4.
J Mol Biol. 2010 Aug 20;401(3):389-402. doi: 10.1016/j.jmb.2010.06.017. Epub 2010 Jun 16.
6
Fbxo45, a novel ubiquitin ligase, regulates synaptic activity.
J Biol Chem. 2010 Feb 5;285(6):3840-3849. doi: 10.1074/jbc.M109.046284. Epub 2009 Dec 7.
7
Control of iron homeostasis by an iron-regulated ubiquitin ligase.
Science. 2009 Oct 30;326(5953):718-21. doi: 10.1126/science.1176333. Epub 2009 Sep 17.
8
The F-box protein FBXO45 promotes the proteasome-dependent degradation of p73.
Oncogene. 2009 Sep 3;28(35):3157-66. doi: 10.1038/onc.2009.177. Epub 2009 Jul 6.
9
Fbxo45 forms a novel ubiquitin ligase complex and is required for neuronal development.
Mol Cell Biol. 2009 Jul;29(13):3529-43. doi: 10.1128/MCB.00364-09. Epub 2009 Apr 27.

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