Inomata T, Eguchi Y, Nakamura T
Zentralbl Veterinarmed A. 1989 Mar;36(3):166-74. doi: 10.1111/j.1439-0442.1989.tb00717.x.
At the 1.6-1.8 cm stages in both male and female bovine fetuses, the anlage of the Müllerian duct was first observed as an elevation of mesothelium on the cranial tip of the mesonephros. The duct extended toward the urogenital sinus in parallel with the Wolffian duct. Its caudal end was solid and was fused with the Wolffian duct at about the level of the middle of the gonadal anlage. Thereafter, the Müllerian duct became gradually independent of the Wolffian duct throughout its whole length. Therefore, it may be that the main part of the Müllerian duct is established by budding from the Wolffian duct. At the 4.3-4.5 cm stages the male Müllerian duct began to degenerate and the female one continued to grow. This suggests that the male Müllerian duct is affected by the Müllerian inhibiting substance at these stages. At the 12.0 cm stage, the female Wolffian duct disappeared. The male Wolffian duct was also much reduced in diameter at this stage, but began to grow again from the 14 cm stage onward.
在雄性和雌性牛胎儿1.6 - 1.8厘米阶段，首先观察到苗勒管原基是中肾颅端间皮的一个隆起。该管道与沃尔夫管平行向泌尿生殖窦延伸。其尾端是实心的，在性腺原基中部水平左右与沃尔夫管融合。此后，苗勒管在其全长逐渐与沃尔夫管分离。因此，苗勒管的主要部分可能是由沃尔夫管出芽形成的。在4.3 - 4.5厘米阶段，雄性苗勒管开始退化，而雌性苗勒管继续生长。这表明在这些阶段雄性苗勒管受到苗勒抑制物质的影响。在12.0厘米阶段，雌性沃尔夫管消失。此时雄性沃尔夫管直径也大幅减小，但从14厘米阶段开始又再次生长。
