Nordström Tanja, Hurtig Tuula, Rodriguez Alina, Savolainen Jukka, Rautio Arja, Moilanen Irma, Taanila Anja, Ebeling Hanna
1 Institute of Health Sciences, University of Oulu, Finland.
2 Institute of Clinical Medicine, Department of Child Psychiatry, University and University Hospital of Oulu, Finland.
J Atten Disord. 2017 Sep;21(11):904-912. doi: 10.1177/1087054714538654. Epub 2014 Jul 7.
To examine different risk factors between disruptive behavior disorders (DBD) and ADHD or combined DBD and ADHD.
The study population was derived from the Northern Finland Birth Cohort 1986. Psychiatric diagnoses were defined from the Schedule for Affective Disorders and Schizophrenia for School-Age Children-Present and Lifetime Version (K-SADS-PL) interview. The study sample was divided into four groups-people with DBD ( n = 44), with ADHD ( n = 91), with both ( n = 72), and without either ( n = 250)-to evaluate the different risk factors behind these disorders.
After adjusting with possible confounding factors, female gender and paternal admittance to inpatient psychiatric care increased the odds that an adolescent was having DBD. Childhood hyperactivity symptoms increased the odds of having ADHD and childhood hyperactivity symptoms and scholastic impairment increased the odds of having both disorders.
Our study indicates DBD and ADHD have clearly different risk factors, and the impact of the paternal factors on DBD should be noted more than has been before.
研究破坏性行为障碍（DBD）与注意力缺陷多动障碍（ADHD）之间，以及合并存在DBD和ADHD时的不同风险因素。
研究人群来自1986年芬兰北部出生队列。精神疾病诊断依据学龄儿童情感障碍和精神分裂症量表（目前和终生版，K-SADS-PL）访谈确定。研究样本分为四组——患有DBD的人（n = 44）、患有ADHD的人（n = 91）、同时患有两者的人（n = 72）以及两者都不患的人（n = 250）——以评估这些疾病背后的不同风险因素。
在对可能的混杂因素进行调整后，女性性别和父亲入住精神病院增加了青少年患DBD的几率。儿童期多动症状增加了患ADHD的几率，而儿童期多动症状和学业障碍增加了同时患两种疾病的几率。
我们的研究表明，DBD和ADHD有明显不同的风险因素，并且父亲因素对DBD的影响应比以往得到更多关注。
