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视网膜动脉阻塞和前部缺血性视神经病变患者的颈内动脉斑块与主动脉弓斑块之间是否存在差异?

[Are there differences between internal carotid artery and aortic arch plaques among patients with retinal artery occlusion and anterior ischaemic optic neuropathy?].

作者信息

Leisser C

机构信息

Augenabteilung, Hanusch-Krankenhaus, Vienna, Austria.

出版信息

Klin Monbl Augenheilkd. 2014 Nov;231(11):1084-7. doi: 10.1055/s-0034-1368574. Epub 2014 Jul 8.

Abstract

INTRODUCTION

Retinal artery occlusion (RAO) and non-arteritic anterior ischaemic optic neuropathy (NAION) cause painless vision deterioration and visual field defects. Associations with arteriosclerotic risk factors, hyperhomocysteinaemia, hyperfibrinogenaemia and plaques of the internal carotid artery are well kown. Results of transoesophageal echocardiography with respect to plaques in the aortic arch and duplex sonography of the internal carotid artery were evaluated and a statistical analysis was performed.

MATERIAL AND METHODS

110 patients with RAO and 49 patients with NAION were retrospectively analysed. Statistical significant differences were analysed with the Mann-Whitney test (U test) using SPSS 13.0 (IBM).

RESULTS

RAO patients have statistically significantly more often plaques in the aortic arch, medium-sized plaques of the internal carotid artery, a history of stroke and hyperhomocysteinaemia. NAION patients have statistically significantly more often small plaques of the internal carotid artery. All other parameters do not show statistically significant differences between both diseases.

CONCLUSIONS

RAO patients have a higher median age and seem to have more often arteriosclerotic plaques in the aortic arch and larger plaques in the internal carotid artery than NAION patients, although both diseases show comparable associations with arteriosclerotic risk factors.

摘要

引言

视网膜动脉阻塞(RAO)和非动脉炎性前部缺血性视神经病变(NAION)会导致无痛性视力下降和视野缺损。与动脉粥样硬化危险因素、高同型半胱氨酸血症、高纤维蛋白原血症以及颈内动脉斑块的关联已广为人知。对经食管超声心动图检查主动脉弓斑块的结果以及颈内动脉双功超声检查结果进行了评估,并进行了统计分析。

材料与方法

对110例视网膜动脉阻塞患者和49例非动脉炎性前部缺血性视神经病变患者进行回顾性分析。使用SPSS 13.0(IBM)软件通过曼-惠特尼检验(U检验)分析统计学上的显著差异。

结果

视网膜动脉阻塞患者在主动脉弓出现斑块、颈内动脉中等大小斑块、有中风病史和高同型半胱氨酸血症的情况在统计学上更为常见。非动脉炎性前部缺血性视神经病变患者颈内动脉小斑块在统计学上更为常见。两种疾病在所有其他参数上均未显示出统计学上的显著差异。

结论

视网膜动脉阻塞患者的年龄中位数较高,与非动脉炎性前部缺血性视神经病变患者相比,似乎更常出现主动脉弓动脉粥样硬化斑块以及颈内动脉较大斑块,尽管两种疾病与动脉粥样硬化危险因素的关联相当。

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