Brockow Knut, Sánchez-Borges Mario
Department of Dermatology and Allergy Biederstein, Technische Universität München, Biedersteiner Strasse 29, Munich 80802, Germany.
Allergy and Clinical Immunology Department, Centro Médico Docente La Trinidad, Clínica El Avila, 6a transversal de Altamira, piso 8, consultorio 803, Caracas 1060, Venezuela.
Immunol Allergy Clin North Am. 2014 Aug;34(3):547-64, viii. doi: 10.1016/j.iac.2014.04.002.
This article updates current knowledge on hypersensitivity reactions to diagnostic contrast media and dyes. After application of a single iodinated radiocontrast medium (RCM), gadolinium-based contrast medium, fluorescein, or a blue dye, a hypersensitivity reaction is not a common finding; however, because of the high and still increasing frequency of those procedures, patients who have experienced severe reactions are nevertheless frequently encountered in allergy departments. Evidence on allergologic testing and management is best for iodinated RCM, limited for blue dyes, and insufficient for fluorescein. Skin tests can be helpful in the diagnosis of patients with hypersensitivity reactions to these compounds.
本文更新了关于诊断性造影剂和染料超敏反应的现有知识。在应用单一碘化放射造影剂（RCM）、钆基造影剂、荧光素或蓝色染料后，超敏反应并不常见；然而，由于这些检查的频率高且仍在增加，过敏科仍经常遇到经历过严重反应的患者。关于变应性检测和管理的证据，碘化RCM最为充分，蓝色染料有限，荧光素则不足。皮肤试验有助于诊断对这些化合物发生超敏反应的患者。
