Sato K, Mimura M
Kansenshogaku Zasshi. 1989 Mar;63(3):189-94. doi: 10.11150/kansenshogakuzasshi1970.63.189.
Five cases of penicillin insensitive or resistant pneumococcal infection in children were experienced during the period of 2 years since March, 1986. One isolate from middle ear showed the MIC of 4 micrograms/ml against penicillin-G. One isolate of insensitive pneumococcus was isolated from CSF specimen. Between 1976 and 1987, 59 isolates from 88 stocked pneumococcal clinical isolates were alive. These 59 strains were screened by oxacillin disc for insensitive and resistant pneumococcus. Five strains which were insensitive or resistant strains had inhibitory zone under 20 mm. The prevalence rate of insensitive or resistant pneumococcus since 1986 was 18%.