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喉罩自主呼吸麻醉下非气管插管胸腔镜肺结节切除术

Nonintubated thoracoscopic pulmonary nodule resection under spontaneous breathing anesthesia with laryngeal mask.

作者信息

Ambrogi Marcello C, Fanucchi Olivia, Korasidis Stylianos, Davini Federico, Gemignani Raffaello, Guarracino Fabio, Melfi Franca, Mussi Alfredo

机构信息

From the *Division of Thoracic Surgery, Department of Surgical, Medical, Molecular, and Critical Area Pathology, University of Pisa; †Division of Thoracic Surgery, CardioThoracic and Vascular Department, and ‡Division of Anesthesiology and Intensive Care, Department of Anesthesiology and Intensive Care, Azienda Ospedaliero-Universitaria Pisana, Pisa, Italy.

出版信息

Innovations (Phila). 2014 Jul-Aug;9(4):276-80. doi: 10.1097/IMI.0000000000000075.

Abstract

OBJECTIVE

During the past 20 years, the use of video-assisted thoracoscopic surgery has increased as an important minimally invasive tool. To further reduce its invasiveness, after a preliminary experience, we decided to use a nonintubated spontaneous breathing general anesthesia, for video-assisted thoracoscopic surgery resection of lung nodule, using a laryngeal mask (LMA). This study aimed to verify the safety and the feasibility of this technique.

METHODS

Twenty consecutive patients who underwent thoracoscopic wedge of lung nodule under spontaneous breathing general anesthesia with LMA are the subjects of this study. Clinical data, American Society of Anesthesiologists status, Adult Comorbidity Evaluation-27 score, and Revised Cardiac Risk Index score were recorded for each patient. General inhalatory anesthesia (sevoflurane) was given in all cases through an LMA, without muscle relaxants, thus allowing spontaneous breathing. All procedures were performed in the lateral decubitus position. The maximum and minimum values of end-tidal carbon dioxide tension and oxygen saturation were recorded during the procedure. The level of technical feasibility was stratified by the operating surgeon according to four levels: excellent, good, satisfactory, and unsatisfactory.

RESULTS

There were 13 men and 7 women (mean age, 57 years). The mean induction anesthesia time was 6 minutes, whereas the mean operative time was 38 minutes. The values of oxygen saturation as well as minimum and maximum end-tidal carbon dioxide tension were 99.1%, 33.6 mm Hg, and 39.1 mm Hg, respectively. No mask displacement occurred. The mean operative time was 38 minutes (range, 25-90 minutes). The level of technical feasibility was defined as excellent in 19 cases and good in 1 case. No mortality occurred. Morbidity consisted of pleural effusion (one case), which was medically resolved. The mean postoperative stay was 3.5 days. Histopathologic results were one squamous cell lung cancer (lung primary), one adenocarcinoma (lung primary), five metastasis from colon cancer, four metastasis from breast cancer, three metastasis from renal cancer, three sarcoidosis, two amartocondroma, and one tuberculosis.

CONCLUSIONS

Our experience suggests that thoracoscopic wedge resection of lung nodule is safe and feasible under spontaneous breathing anesthesia with LMA. This technique permits a confident manipulation of lung parenchyma and a safe stapler positioning, without cough, pain, or panic attack described for awake epidural anesthesia, avoiding the risks related to tracheal intubation and mechanical ventilation.

摘要

目的

在过去20年中,电视辅助胸腔镜手术作为一种重要的微创工具,其应用有所增加。为了进一步降低其侵入性,在初步经验之后,我们决定使用喉罩(LMA)进行非插管自主呼吸全身麻醉,用于电视辅助胸腔镜手术切除肺结节。本研究旨在验证该技术的安全性和可行性。

方法

本研究的对象为20例连续接受在LMA自主呼吸全身麻醉下进行胸腔镜肺结节楔形切除术的患者。记录每位患者的临床资料、美国麻醉医师协会分级、成人合并症评估-27评分和修订心脏风险指数评分。所有病例均通过LMA给予全身吸入麻醉(七氟醚),不使用肌肉松弛剂,从而允许自主呼吸。所有手术均在侧卧位进行。术中记录呼气末二氧化碳分压和氧饱和度的最大值和最小值。手术医生根据四个级别对技术可行性水平进行分层:优秀、良好、满意和不满意。

结果

男性13例,女性7例(平均年龄57岁)。平均诱导麻醉时间为6分钟,而平均手术时间为38分钟。氧饱和度以及呼气末二氧化碳分压的最小值和最大值分别为99.1%、33.6 mmHg和39.1 mmHg。未发生面罩移位。平均手术时间为38分钟(范围25 - 90分钟)。技术可行性水平被定义为19例优秀,1例良好。无死亡发生。并发症包括胸腔积液(1例),经药物治疗后缓解。平均术后住院时间为3.5天。组织病理学结果为1例肺鳞状细胞癌(原发性肺癌)、1例腺癌(原发性肺癌)、5例结肠癌转移、4例乳腺癌转移、3例肾癌转移、3例结节病、2例错构瘤和1例肺结核。

结论

我们的经验表明,在LMA自主呼吸麻醉下进行胸腔镜肺结节楔形切除术是安全可行的。该技术允许对肺实质进行可靠的操作和安全的吻合器定位,没有清醒硬膜外麻醉所描述的咳嗽、疼痛或惊恐发作,避免了与气管插管和机械通气相关的风险。

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