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疑似细菌性脑膜炎诊断和治疗中对医疗标准的遵循。

Adherence to standard of care in the diagnosis and treatment of suspected bacterial meningitis.

作者信息

Chia David, Yavari Youness, Kirsanov Eugeny, Aronin Steven I, Sadigh Majid

机构信息

Waterbury Hospital, Waterbury, CT

Danbury Hospital, Danbury, CT.

出版信息

Am J Med Qual. 2015 Nov-Dec;30(6):539-42. doi: 10.1177/1062860614545778. Epub 2014 Aug 1.

Abstract

Acute bacterial meningitis (ABM) is a rare but deadly neurological emergency. Accordingly, Infectious Diseases Society of America (IDSA) guidelines summarize current evidence into a straightforward algorithm for its management. The goal of this study is to evaluate the overall compliance with these guidelines in patients with suspected ABM. A retrospective cross-sectional study was conducted of adult patients who underwent lumbar puncture for suspected ABM to ascertain local adherence patterns to IDSA guidelines for bacterial meningitis. Primary outcomes included appropriate utilization of neuroimaging, blood cultures, antibiotics, corticosteroids, and lumbar puncture. In all, 160 patients were included in the study. Overall IDSA compliance was only 0.6%. Neuroimaging and blood cultures were appropriately utilized in 54.3% and 47.5% of patients, respectively. Steroids and antibiotics were appropriately administered in only 7.5% and 5.6% of patients, respectively. Adherence to IDSA guidelines is poor. Antibiotic choice is often incorrect, corticosteroids are rarely administered, and there is an overutilization of neuroimaging.

摘要

急性细菌性脑膜炎(ABM)是一种罕见但致命的神经系统急症。因此,美国传染病学会(IDSA)指南将当前证据总结为一种简单明了的管理算法。本研究的目的是评估疑似ABM患者对这些指南的总体遵循情况。对因疑似ABM接受腰椎穿刺的成年患者进行了一项回顾性横断面研究,以确定当地对IDSA细菌性脑膜炎指南的遵循模式。主要结局包括神经影像学检查、血培养、抗生素、皮质类固醇和腰椎穿刺的合理应用。该研究共纳入160例患者。IDSA指南的总体遵循率仅为0.6%。分别有54.3%和47.5%的患者合理使用了神经影像学检查和血培养。仅分别有7.5%和5.6%的患者合理使用了类固醇和抗生素。对IDSA指南的遵循情况较差。抗生素选择往往不正确,皮质类固醇很少使用,并且神经影像学检查存在过度使用的情况。

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