Chen Jun, Weinstein Jeffrey, Black Sylvester, Spain James, Brady Paul S, Dowell Joshua D
Division of Interventional Radiology, Department of Radiology, Wexner Medical Center, The Ohio State University, Columbus, OH, USA.
Clin Transplant. 2014 Dec;28(12):1305-12. doi: 10.1111/ctr.12431. Epub 2014 Aug 22.
Vascular complications after liver transplantation increase post-operative morbidity and contribute to the incidence of retransplantation. Vascular complications comprise arterial, caval, and portal venous pathology, with the majority of complications being arterial in etiology, including anastomotic stricture, pseudoaneurysm, and thrombosis. There are two major therapeutic options for the treatment of these arterial complications: endovascular intervention and surgery. The former includes intra-arterial thrombolysis, embolization, percutaneous transluminal angioplasty, and stent placement. The latter includes thrombectomy, reanastomosis, and retransplantation. Although surgical treatment has been considered the first choice for management in the past, advances in endovascular intervention have increased and make it a viable therapeutic option following orthotopic liver transplantation. This review focuses on the role of surgical and endovascular therapy in the management of hepatic arterial complications after liver transplantation.
肝移植后的血管并发症会增加术后发病率,并导致再次移植的发生率升高。血管并发症包括动脉、腔静脉和门静脉病变,其中大多数并发症的病因是动脉性的,包括吻合口狭窄、假性动脉瘤和血栓形成。治疗这些动脉并发症有两种主要的治疗选择:血管内介入治疗和手术治疗。前者包括动脉内溶栓、栓塞、经皮腔内血管成形术和支架置入术。后者包括血栓切除术、再次吻合术和再次移植术。尽管过去手术治疗一直被认为是首选的治疗方法,但血管内介入治疗的进展增加了,使其成为原位肝移植后一种可行的治疗选择。本综述重点关注手术和血管内治疗在肝移植后肝动脉并发症管理中的作用。