视觉性眩晕和前庭病变对眼球运动反应的影响。

The influence of visual vertigo and vestibulopathy on oculomotor responses.

作者信息

Zur Oz, Dickstein Ruth, Dannenbaum Elizabeth, Carmeli Eli, Fung Joyce

机构信息

Department of Physical Therapy, Faculty of Social Welfare and Health Sciences, University of Haifa, Haifa, Israel.

Physical Therapy Services, Flieman Geriatric Rehabilitation Hospital, Haifa, Israel.

出版信息

J Vestib Res. 2014;24(4):305-11. doi: 10.3233/VES-140519.

DOI:10.3233/VES-140519

PMID:25095775

Abstract

OBJECTIVE

Dynamic visual inputs can cause visual vertigo (VV) in patients with vestibulopathy, leading to dizziness and falls. This study investigated the influence of VV on oculomotor responses.

METHODS

In this cross-sectional, single-blind study, with experimental and control groups, 8 individuals with vestibulopathy and VV, 10 with vestibulopathy and no VV, and 10 healthy controls participated. Oculomotor responses were examined with 2-dimensional video-oculography. Participants were exposed to dynamic visual inputs of vertical stripes sweeping across a screen at 20 deg/sec, while seated or in Romberg stance, with and without a fixed target. Responses were quantified by optokinetic nystagmus frequency (OKNf) and gain (OKNg).

RESULTS

Seated with no target, VV participants had higher OKNf than controls (37 ± 9 vs. 24 ± 9 peaks/sec; P < 0.05). In Romberg stance with no target, they had higher OKNf than controls (41 ± 9 vs. 28 ± 10 peaks/sec; P < 0.05). With a target, OKNf was higher in VV participants compared to controls (7 ± 7 vs. 1 μ 2 peaks/sec; P < 0.05). In Romberg with no target, OKNg was higher in the VV group (0.8 ± 0.1) compared to controls (0.6 ± 0.2; P=0.024). OKNf and OKNg did not differ according to VV status.

CONCLUSIONS

VV participants had increased OKNf and OKNg compared to healthy participants. Visual dependency should be considered in vestibular rehabilitation.

摘要

目的

动态视觉输入可导致前庭病变患者出现视觉性眩晕（VV），进而引起头晕和跌倒。本研究调查了VV对眼动反应的影响。

方法

在这项横断面单盲研究中，设有实验组和对照组，8例患有前庭病变并伴有VV的个体、10例患有前庭病变但无VV的个体以及10名健康对照者参与。使用二维视频眼震图检查眼动反应。参与者坐在椅子上或处于闭目直立姿势时，在有和没有固定目标的情况下，暴露于以20度/秒速度在屏幕上横扫的垂直条纹的动态视觉输入中。通过视动性眼震频率（OKNf）和增益（OKNg）对反应进行量化。

结果

在没有目标的坐姿下，患有VV的参与者的OKNf高于对照组（37±9对24±9次/秒；P<0.05）。在没有目标的闭目直立姿势下，他们的OKNf高于对照组（41±9对28±10次/秒；P<0.05）。有目标时，患有VV的参与者的OKNf高于对照组（7±7对1±2次/秒；P<0.05）。在没有目标的闭目直立姿势下，VV组的OKNg高于对照组（0.8±0.1对0.6±0.2；P=0.024）。OKNf和OKNg根据VV状态没有差异。