Nishi S, Hanakita J, Suwa H, Ohta F, Sakaida H
Department of Neurosurgery, Shizuoka General Hospital, Japan.
No Shinkei Geka. 1989 Oct;17(10):953-7.
Multiple spinal tumors are relatively rare and account for from only 1.2 to 9.5% of all spinal tumors. Half of the multiple spinal tumors are accompanied with von Recklinghausen's disease. Since March 1983, we have encountered 31 spinal tumors including 11 neurinomas, three of which were multiple and showed no manifestations of von Recklinghausen's disease. The incidence of multiple spinal tumors was 9.7% in our series. Altogether, 40 cases of multiple spinal neurinomas without von Recklinghausen's disease have been reported including our three cases. According to those 40 cases, much neurinomas occur 5 times more frequently in men than in women, and they are found predominantly in the lumbosacral region. In the present paper, we describe three cases of multiple spinal neurinomas, and compare the results of several neuroradiological examinations. Myelography was the most reliable method to determine whether or not the tumors were multiple. However, in cases where myelography was completely blocked out, other neuroradiological methods such as metrizamide-CT scan or MRI with Gd-DTPA intravenous injection were able to bring us information concerning multiplicity.
多发性脊柱肿瘤相对少见,仅占所有脊柱肿瘤的1.2%至9.5%。半数多发性脊柱肿瘤伴有冯雷克林霍增氏病。自1983年3月以来,我们共收治31例脊柱肿瘤,其中神经鞘瘤11例,3例为多发且无冯雷克林霍增氏病表现。在我们的病例系列中,多发性脊柱肿瘤的发生率为9.7%。包括我们的3例病例在内,总共已有40例无冯雷克林霍增氏病的多发性脊柱神经鞘瘤的报道。根据这40例病例,男性多发性神经鞘瘤的发生率比女性高5倍,且主要发生于腰骶部。在本文中,我们描述3例多发性脊柱神经鞘瘤病例,并比较几种神经放射学检查的结果。脊髓造影是确定肿瘤是否为多发的最可靠方法。然而,在脊髓造影完全梗阻的病例中,其他神经放射学方法,如甲泛葡胺CT扫描或静脉注射钆喷酸葡胺的MRI检查,能够为我们提供有关肿瘤多发性的信息。