神经刺激的合理应用:颅内、颅外空间及头部刺激用于慢性疼痛。神经调节适宜性共识委员会。
The appropriate use of neurostimulation: stimulation of the intracranial and extracranial space and head for chronic pain. Neuromodulation Appropriateness Consensus Committee.
作者信息
Deer Timothy R, Mekhail Nagy, Petersen Erika, Krames Elliot, Staats Peter, Pope Jason, Saweris Youssef, Lad Shivanand P, Diwan Sudhir, Falowski Steven, Feler Claudio, Slavin Konstantin, Narouze Samer, Merabet Lotfi, Buvanendran Asokumar, Fregni Felipe, Wellington Joshua, Levy Robert M
机构信息
Center for Pain Relief, Charleston, WV, USA.
出版信息
Neuromodulation. 2014 Aug;17(6):551-70; discussion 570. doi: 10.1111/ner.12215.
INTRODUCTION
The International Neuromodulation Society (INS) has identified a need for evaluation and analysis of the practice of neurostimulation of the brain and extracranial nerves of the head to treat chronic pain.
METHODS
The INS board of directors chose an expert panel, the Neuromodulation Appropriateness Consensus Committee (NACC), to evaluate the peer-reviewed literature, current research, and clinical experience and to give guidance for the appropriate use of these methods. The literature searches involved key word searches in PubMed, EMBASE, and Google Scholar dated 1970-2013, which were graded and evaluated by the authors.
RESULTS
The NACC found that evidence supports extracranial stimulation for facial pain, migraine, and scalp pain but is limited for intracranial neuromodulation. High cervical spinal cord stimulation is an evolving option for facial pain. Intracranial neurostimulation may be an excellent option to treat diseases of the nervous system, such as tremor and Parkinson's disease, and in the future, potentially Alzheimer's disease and traumatic brain injury, but current use of intracranial stimulation for pain should be seen as investigational.
CONCLUSIONS
The NACC concludes that extracranial nerve stimulation should be considered in the algorithmic treatment of migraine and other disorders of the head. We should strive to perfect targets outside the cranium when treating pain, if at all possible.
引言
国际神经调节学会(INS)已确定有必要对脑部及头部颅外神经的神经刺激疗法治疗慢性疼痛的实践进行评估和分析。
方法
INS董事会挑选了一个专家小组,即神经调节适宜性共识委员会(NACC),来评估经同行评审的文献、当前研究及临床经验,并为这些方法的合理应用提供指导。文献检索涉及在PubMed、EMBASE和谷歌学术中进行关键词检索,检索时间为1970年至2013年,由作者对检索结果进行分级和评估。
结果
NACC发现,有证据支持颅外刺激用于治疗面部疼痛、偏头痛和头皮疼痛,但颅内神经调节的证据有限。高位颈脊髓刺激是治疗面部疼痛的一种不断发展的选择。颅内神经刺激可能是治疗神经系统疾病(如震颤和帕金森病)的极佳选择,未来可能还适用于阿尔茨海默病和创伤性脑损伤,但目前将颅内刺激用于疼痛治疗应视为试验性的。
结论
NACC得出结论,在偏头痛和其他头部疾病的算法治疗中应考虑颅外神经刺激。如果可能的话,在治疗疼痛时我们应努力完善颅外靶点。