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[Delayed anaphylaxis after ingestion of meat. Carbohydrate epitope galactose-α-1,3-galactose as cause of severe anaphylactic reactions].

作者信息

Soemantri S P, Höxtermann S, Holz-Larose R, Altmeyer P, Dickel H

机构信息

Klinik für Dermatologie, Venerologie und Allergologie der Ruhr-Universität Bochum, St. Josef-Hospital, Gudrunstraße 56, 44791, Bochum, Deutschland.

出版信息

Hautarzt. 2015 Feb;66(2):117-20. doi: 10.1007/s00105-014-3504-x.

Abstract

The correlation between anaphylaxis after consumption of meat and the carbohydrate epitope galactose-α-1,3-galactose (α-Gal) was first described in oncologic patients treated with cetuximab. An association with tick bites and parasitosis is suspected. We report on a healthy patient who developed sudden anaphylactic reactions after the ingestion of meat. Serologic and skin tests confirmed sensitization to α-Gal. Avoiding the consumption of mammalian meat led to a complete absence of symptoms.

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