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Targeting inhibitor of apoptosis proteins for cancer therapy: a double-edge sword?

作者信息

Fulda Simone

机构信息

Goethe-University, Frankfurt, Germany

出版信息

J Clin Oncol. 2014 Oct 1;32(28):3190-1. doi: 10.1200/JCO.2014.56.8741. Epub 2014 Aug 11.

DOI:10.1200/JCO.2014.56.8741

PMID:25113757

Abstract

摘要

相似文献

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Targeting inhibitor of apoptosis proteins for cancer therapy: a double-edge sword?

作者信息

Fulda Simone

机构信息

Goethe-University, Frankfurt, Germany

出版信息

J Clin Oncol. 2014 Oct 1;32(28):3190-1. doi: 10.1200/JCO.2014.56.8741. Epub 2014 Aug 11.

DOI:10.1200/JCO.2014.56.8741

PMID:25113757

Abstract

摘要

相似文献

Targeting inhibitor of apoptosis proteins for cancer therapy: a double-edge sword?

J Clin Oncol. 2014 Oct 1;32(28):3190-1. doi: 10.1200/JCO.2014.56.8741. Epub 2014 Aug 11.

IAP antagonists: promising candidates for cancer therapy.

Drug Discov Today. 2010 Mar;15(5-6):210-9. doi: 10.1016/j.drudis.2010.01.003. Epub 2010 Jan 21.

Targeting inhibitor of apoptosis proteins for therapeutic intervention.

Future Med Chem. 2009 Nov;1(8):1509-25. doi: 10.4155/fmc.09.116.

The IAP Protein Family, SMAC Mimetics and Cancer Treatment.

Crit Rev Oncog. 2016;21(3-4):185-202. doi: 10.1615/CritRevOncog.2016017032.

Drug insight: cancer therapy strategies based on restoration of endogenous cell death mechanisms.

Nat Clin Pract Oncol. 2006 Jul;3(7):388-98. doi: 10.1038/ncponc0538.

Targeting apoptosis pathways for new cancer therapeutics.

Annu Rev Med. 2014;65:139-55. doi: 10.1146/annurev-med-010713-141310. Epub 2013 Nov 4.

Thioproline and reversal of cancer.

Lancet. 1983 May 14;1(8333):1108. doi: 10.1016/s0140-6736(83)91947-5.

[Advances in studies on inhibitor of apoptosis proteins and cancer therapy].

Yao Xue Xue Bao. 2006 Feb;41(2):103-7.

Promises and Challenges of Smac Mimetics as Cancer Therapeutics.

Clin Cancer Res. 2015 Nov 15;21(22):5030-6. doi: 10.1158/1078-0432.CCR-15-0365.

SNS-595, a naphthyridine cell cycle inhibitor and stimulator of apoptosis for the treatment of cancers.

Curr Opin Investig Drugs. 2008 Jun;9(6):647-57.

引用本文的文献

The expanding role of IAP antagonists for the treatment of head and neck cancer.

Cancer Med. 2023 Jul;12(13):13958-13965. doi: 10.1002/cam4.6011. Epub 2023 May 2.

Final results of a phase 2 clinical trial of LCL161, an oral SMAC mimetic for patients with myelofibrosis.

Blood Adv. 2021 Aug 24;5(16):3163-3173. doi: 10.1182/bloodadvances.2020003829.

Smac-mimetics reduce numbers and viability of human osteoclasts.

Cell Death Discov. 2021 Feb 19;7(1):36. doi: 10.1038/s41420-021-00415-1.

Curcumol Exerts Anticancer Effect in Cholangiocarcinoma Cells via Down-Regulating CDKL3.

Front Physiol. 2018 Mar 20;9:234. doi: 10.3389/fphys.2018.00234. eCollection 2018.

Unlocking the NF-κB Conundrum: Embracing Complexity to Achieve Specificity.

Biomedicines. 2017 Aug 22;5(3):50. doi: 10.3390/biomedicines5030050.

UBXD Proteins: A Family of Proteins with Diverse Functions in Cancer.

Int J Mol Sci. 2016 Oct 14;17(10):1724. doi: 10.3390/ijms17101724.

The SMAC mimetic, LCL-161, reduces survival in aggressive MYC-driven lymphoma while promoting susceptibility to endotoxic shock.

Oncogenesis. 2016 Apr 4;5(4):e216. doi: 10.1038/oncsis.2016.26.

Knockdown of autophagy-related protein 6, Beclin-1, decreases cell growth, invasion, and metastasis and has a positive effect on chemotherapy-induced cytotoxicity in osteosarcoma cells.

Tumour Biol. 2015 Apr;36(4):2531-9. doi: 10.1007/s13277-014-2868-y. Epub 2014 Nov 27.