Ay Yasin, Erkin Alper, Kara Ibrahim, Aydin Cemalettin, Ay Nuray Kahraman, Zeybek Rahmi
Department of Cardiovascular Surgery, Bezmialem Vakif University, Istanbul, Turkey.
Department of Cardiovascular Surgery, Sakarya University School of Medicine, Sakarya, Turkey.
Asian Cardiovasc Thorac Ann. 2015 Jun;23(5):517-24. doi: 10.1177/0218492314547088. Epub 2014 Aug 10.
To evaluate the medium-term results of plication of posterior leaflet segment 2 in addition to ring annuloplasty in patients with functional ischemic mitral regurgitation.
The study included 136 patients who underwent mitral valve repair with plication of posterior leaflet segment 2 for ischemic mitral regurgitation between 2004 and 2012. The direction and correlation of left ventricle sphericity and tethering area were established by Pearson correlation analysis in patients with or without recurrent mitral regurgitation in the medium term.
Medium-term survival was 91.9% and freedom from moderate or severe mitral regurgitation was 89.6%. In medium-term follow-up, transthoracic echocardiography found a significant decrease in tethering area, coaptation height, and distance between the commissures compared to the pre-surgery values (p = 0.0001 in all). The distance between the papillary muscles was reduced compared to the pre-surgery period but it was not significant (p = 0.204). Pearson correlation analysis found no significant correlation between the tethering area and left ventricle sphericity in patients without recurrent mitral regurgitation (r = 0.15, p = 0.36), a highly positive correlation (r = 0.44, p < 0.001) in patients with mild recurrent mitral regurgitation, and a moderately positive correlation (r = 0.71, p < 0.01) in patients with moderate or severe recurrent mitral regurgitation.
The tethering area, coaptation height, and distance between the commissures decreased significantly, thus posterior leaflet segment 2 plication in addition to ring annuloplasty may be the optional procedure to ensure freedom from moderate or severe mitral regurgitation.
评估在功能性缺血性二尖瓣反流患者中,除了进行瓣环成形术外,对后叶2段进行折叠术的中期效果。
该研究纳入了2004年至2012年间因缺血性二尖瓣反流接受二尖瓣修复并对后叶2段进行折叠术的136例患者。通过Pearson相关性分析确定中期有无复发性二尖瓣反流患者左心室球形度与瓣叶牵拉面积的方向及相关性。
中期生存率为91.9%,无中度或重度二尖瓣反流的比例为89.6%。在中期随访中,经胸超声心动图显示,与术前值相比,瓣叶牵拉面积、瓣叶对合高度和瓣叶交界间距离均显著减小(均p = 0.0001)。与术前相比,乳头肌间距离减小,但差异无统计学意义(p = 0.204)。Pearson相关性分析发现,无复发性二尖瓣反流患者的瓣叶牵拉面积与左心室球形度无显著相关性(r = 0.15,p = 0.36);轻度复发性二尖瓣反流患者呈高度正相关(r = 0.44,p < 0.001);中度或重度复发性二尖瓣反流患者呈中度正相关(r = 0.71,p < 0.01)。
瓣叶牵拉面积、瓣叶对合高度和瓣叶交界间距离显著减小,因此除瓣环成形术外,对后叶2段进行折叠术可能是确保无中度或重度二尖瓣反流的可选术式。