Xu Hairong, Niu Xiaohui, Li Yuan, Binitie Odion T, Letson G Douglas, Cheong David
Department of Orthopedic Oncology Surgery, Beijing Ji Shui Tan Hospital, Peking University, Beijing, China.
Clin Orthop Relat Res. 2014 Nov;472(11):3462-7. doi: 10.1007/s11999-014-3771-y. Epub 2014 Aug 13.
Treatment of chondroblastoma in the femoral head is challenging owing to the particular location and its aggressive nature. There is little published information to guide the surgeon regarding the appropriate approach to treating a chondroblastoma in this location. We developed a modified trapdoor procedure to address this issue. The primary modification is that the window surface of the femoral head is covered by the ligamentum teres rather than cartilage as in the traditional procedure.
QUESTIONS/PURPOSES: We assessed (1) the clinical presentation of chondroblastoma of the femoral head and treatment results with the modified trapdoor procedure in terms of (2) the frequency of local recurrence, (3) complications, and (4) functional outcomes using the Musculoskeletal Tumor Society (MSTS) score.
Between 1999 and 2010, we treated 14 patients for chondroblastoma of the femoral head. All patients received the modified trapdoor procedure. Of those, 13 were available for followup at a minimum of 36 months (mean, 66 months; range, 36-117 months) and one patient was lost to followup. There were nine males and four females, with a mean age of 18 years (range, 9-29 years). Clinical features were ascertained by chart and radiographic review, and recurrence, complications, and functional outcomes (MSTS score) were recorded from chart review. Patterns of bone destruction were evaluated using the Lodwick classification, which ranges from IA (geographic appearance with sclerotic rim) to III (permeative appearance).
The symptoms at diagnosis were pain in nine patients and discomfort in four. The mean duration of symptom was 11 months (range, 1-36 months). The physis was open in two patients, closing in one, and closed in 10. The patterns of bone destruction were evaluated as Lodwick Class IA in six patients, Lodwick Class IB in five, and Lodwick Class IC in two. At latest followup, no local recurrence was observed. Two patients had postoperative complications. One had avascular necrosis of the femoral head and was treated with prosthesis replacement. The other had asymptomatic heterotopic ossification in the surgical field. The mean MSTS score was 29.6 (range, 28-30).
Based on this small series, we believe our modified trapdoor procedure is a safe, effective means of treating a chondroblastoma in the femoral head, but additional clinical evaluation with more patients is necessary to confirm our findings.
Level IV, therapeutic study. See the Instructions for Authors for a complete description of levels of evidence.
由于股骨头部位特殊且成软骨细胞瘤具有侵袭性,因此股骨头成软骨细胞瘤的治疗颇具挑战性。关于如何恰当治疗该部位成软骨细胞瘤,几乎没有公开的信息可供外科医生参考。我们研发了一种改良活板门手术来解决这一问题。主要的改良之处在于,与传统手术不同,股骨头的开窗表面由圆韧带覆盖而非软骨。
问题/目的:我们评估了(1)股骨头成软骨细胞瘤的临床表现以及采用改良活板门手术的治疗结果,具体涉及(2)局部复发频率、(3)并发症以及(4)使用肌肉骨骼肿瘤学会(MSTS)评分的功能结局。
1999年至2010年间,我们治疗了14例股骨头成软骨细胞瘤患者。所有患者均接受了改良活板门手术。其中13例患者获得了至少36个月的随访(平均66个月;范围36 - 117个月),1例患者失访。患者中男性9例,女性4例,平均年龄18岁(范围9 - 29岁)。通过病历和影像学检查确定临床特征,并通过病历回顾记录复发情况、并发症及功能结局(MSTS评分)。采用Lodwick分类法评估骨破坏模式,其范围从IA(具有硬化边缘的地图样表现)到III(浸润性表现)。
诊断时的症状,9例患者为疼痛,4例为不适。症状的平均持续时间为11个月(范围1 - 36个月)。2例患者的骨骺未闭合,1例骨骺正在闭合,10例骨骺已闭合。骨破坏模式评估为Lodwick IA级的有6例患者,Lodwick IB级的有5例,Lodwick IC级的有2例。在最近一次随访时,未观察到局部复发。2例患者出现术后并发症。1例发生股骨头缺血性坏死,接受了假体置换治疗。另1例在手术区域出现无症状性异位骨化。MSTS评分的平均值为29.6(范围28 - 30)。
基于这个小样本系列研究,我们认为我们的改良活板门手术是治疗股骨头成软骨细胞瘤的一种安全、有效的方法,但需要更多患者的进一步临床评估来证实我们的发现。
IV级,治疗性研究。有关证据水平的完整描述,请参阅作者指南。