Stem Cell Institute and Division of Pediatric Blood and Marrow Transplantation, University of Minnesota, Minneapolis, Minnesota, USA.
St John's Institute of Dermatology, King's College, London (Guy's Campus), London, UK.
J Invest Dermatol. 2014 Sep;134(9):2312-2314. doi: 10.1038/jid.2014.209.
Novel therapeutic tools to accelerate wound healing would have a major impact on the overall burden of skin disease. Lin et al. demonstrate in mice that endogenous bone marrow stem cell mobilization, produced by a pharmacologic combination of AMD3100 and tacrolimus, leads to faster and better-quality wound healing, findings that have exciting potential for clinical translation.
新型治疗手段加速伤口愈合，将对皮肤病的整体负担产生重大影响。Lin 等人在小鼠中证明，通过 AMD3100 和他克莫司的药物联合使用，诱导内源性骨髓干细胞动员，可实现更快、更高质量的伤口愈合，这一发现为临床转化带来了令人兴奋的潜力。
Zotero 插件