School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, & Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, China; Research Institute for the Changing Global Environment and Fudan Tyndall Centre, Fudan University, Shanghai, China; Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Fudan University, Shanghai, China.
School of Public Health, Key Lab of Public Health Safety of the Ministry of Education, & Key Lab of Health Technology Assessment of the Ministry of Health, Fudan University, Shanghai, China; Research Institute for the Changing Global Environment and Fudan Tyndall Centre, Fudan University, Shanghai, China; Shanghai Key Laboratory of Atmospheric Particle Pollution and Prevention (LAP(3)), Fudan University, Shanghai, China.
Environ Res. 2014 Oct;134:127-33. doi: 10.1016/j.envres.2014.07.007. Epub 2014 Aug 13.
Few multicity studies have been conducted to investigate the acute health effects of cold and hot temperatures in China. We aimed to examine the relationship between temperature and daily mortality in 17 large Chinese cities. We first calculated city-specific effect of temperature using time-series regression models combined with distributed lag nonlinear models; then we pooled the city-specific estimates with the Bayesian hierarchical models. The cold effects lasted longer than the hot effects. For the cold effects, a 1 °C decrease from the 25th to 1st percentiles of temperature over lags 0-14 days was associated with increases of 1.69% [95% posterior intervals (PI): 1.01%, 2.36%], 2.49% (95% PI: 1.53%, 3.46%) and 1.60% (95% PI: 0.32%, 2.87%) in total, cardiovascular and respiratory mortality, respectively. For the hot effects, a 1 °C increase from the 75th to 99th percentiles of temperature was associated with corresponding increases of 2.83% (95% PI: 1.42%, 4.24%), 3.02% (95% PI: 1.33%, 4.71%) and 4.64% (95% PI: 1.96%, 7.31%). The latitudes, number of air conditioning per household and disposable income per capita were significant modifiers for cold effects; the proportion of the elderly was a significant modifier for hot effects. This largest epidemiological study of temperature to date in China suggested that both cold and hot temperatures were associated with increased mortality. Our findings may have important implications for the public health policies in China.
在中国,鲜有针对寒冷和炎热天气对急性健康影响的多城市研究。本研究旨在调查 17 个中国大城市温度与日死亡率之间的关系。我们首先采用时间序列回归模型结合分布式滞后非线性模型计算了各城市的温度效应;然后使用贝叶斯层次模型对各城市的估计值进行了汇总。冷效应持续时间长于热效应。对于冷效应,与温度第 25 百分位到第 1 百分位相比,滞后 0-14 天每降低 1°C,总死亡率、心血管疾病死亡率和呼吸系统死亡率分别增加 1.69%(95%后验区间:1.01%,2.36%)、2.49%(95%后验区间:1.53%,3.46%)和 1.60%(95%后验区间:0.32%,2.87%)。对于热效应,与温度第 75 百分位到第 99 百分位相比,每升高 1°C,总死亡率、心血管疾病死亡率和呼吸系统死亡率分别相应增加 2.83%(95%后验区间:1.42%,4.24%)、3.02%(95%后验区间:1.33%,4.71%)和 4.64%(95%后验区间:1.96%,7.31%)。纬度、每千户家庭空调数量和人均可支配收入是冷效应的显著调节因素;老年人比例是热效应的显著调节因素。这是迄今为止在中国进行的最大规模的与温度相关的流行病学研究,表明寒冷和炎热天气均与死亡率增加有关。我们的研究结果可能对中国的公共卫生政策具有重要意义。