Parda Natalia, Henszel Lukasz, Stępień Małgorzata
Department of Epidemiology, National Institute of Public Health - National Institute of Hygiene (NIZP-PZH) in Warsaw.
Przegl Epidemiol. 2014;68(2):265-9, 369-72.
In Poland, an estimated 2 000 HCV infections are reported annually, of which chronic stage of infections predominates (>95%). It is estimated that seroprevalence of anti-HCV and prevalence of active infections in the general population amount to ca 0.95% (more than 320 000 persons) and 0.6% (230 000 persons), respectively. The alarming finding is that approximately 90% of persons diagnosed with HCV infection are unaware of the condition and consequently hepatitis C virus may be transmitted to their contacts.
The objective of the present article is to determine the epidemiology of HCV infections in Poland in 2012 comparing to the preceding years.
The assessment of epidemiological situation of HCV infections in Poland was based on the analysis of aggregated data from the State Sanitary Inspection, published in "Infectious diseases and poisonings in Poland in 2012" (Czarkowski MP et al. "Infectious diseases and poisonings in Poland in 2012" Warsaw, NIPH-NIH and CSI). The data on mortality due to hepatitis C, which was obtained from the Demographic Surveys and Labour Market Department of Central Statistical Office, were also employed.
In 2012, Poland reported 2 292 HCV infections, meeting 2005 definition (incidence 5.95), of which 1.4% were co-infections with HCV and HBV (33 cases). Compared to the data of 2011, the incidence was slightly lower (2 338; 6.07). Given 2009 definition, a total of 2 265 cases were reported (5.88), which constituted an increase of 3.5% compared to the data from the previous year (2 241; 5.82). Overall, 217 fatal cases due to hepatitis C were reported in 2012, of whom only 9 (4%) were due to acute stage of infection.
Compared to the data from 2011, the epidemiological situation of hepatitis C in Poland has not changed significantly. The alarming fact is the increasing number of deaths due to hepatitis C. Probably, it suggests delayed diagnosis of HCV infections. Thus, it is a necessity to promote early diagnosis of HCV infections which can prevent life and health-threatening sequelae of hepatitis C.
在波兰,每年报告约2000例丙型肝炎病毒(HCV)感染病例,其中感染的慢性阶段占主导(>95%)。据估计,普通人群中抗-HCV血清阳性率和活动性感染患病率分别约为0.95%(超过32万人)和0.6%(23万人)。令人担忧的是,约90%被诊断为HCV感染的人并未意识到自己的病情,因此丙型肝炎病毒可能会传播给他们的接触者。
本文的目的是确定2012年波兰HCV感染的流行病学情况,并与前几年进行比较。
对波兰HCV感染流行病学情况的评估基于对国家卫生检查局汇总数据的分析,这些数据发表在《2012年波兰的传染病和中毒事件》(Czarkowski MP等人,《2012年波兰的传染病和中毒事件》,华沙,国家公共卫生研究所-国家卫生研究院和国家卫生检查局)中。还采用了从中央统计局人口统计与劳动力市场部获得的丙型肝炎相关死亡数据。
2012年,波兰报告了2292例符合2005年定义的HCV感染病例(发病率5.95),其中1.4%为HCV与HBV合并感染(33例)。与2011年的数据相比,发病率略低(2338例;6.07)。按照2009年定义,共报告2265例病例(5.88),与上一年的数据(2241例;5.82)相比增加了3.5%。总体而言,2012年报告了217例丙型肝炎相关死亡病例,其中仅9例(4%)死于感染急性期。
与2011年的数据相比,波兰丙型肝炎的流行病学情况没有显著变化。令人担忧的事实是丙型肝炎相关死亡人数不断增加。这可能表明HCV感染的诊断延迟。因此,有必要推广HCV感染的早期诊断,这可以预防丙型肝炎对生命和健康造成威胁的后遗症。