Zahran Hatice S, Bailey Cathy M, Qin Xiaoting, Moorman Jeanne E
Division of Environmental Hazards and Health Effects, National Center for Environmental Health, Centers for Disease Control and Prevention , Atlanta, GA , USA.
J Asthma. 2015 Apr;52(3):318-26. doi: 10.3109/02770903.2014.956894. Epub 2014 Nov 25.
Monitoring the level of asthma control is important in determining the effectiveness of current treatment which may decrease the frequency and intensity of symptoms and functional limitations. Uncontrolled asthma has been associated with decreased quality of life and increased health care use. The objectives of this study were to assess the level of asthma control and identify related risk factors among persons with current asthma.
Using the 2006 to 2010 BRFSS child and adult Asthma Call-back Survey, asthma control was classified as well-controlled or uncontrolled (not-well-controlled or very-poorly-controlled) using three impairment measures: daytime symptoms, night-time symptoms, and taking short-acting β2-agonists for symptom control. Multivariate logistic regression identified predictors of asthma control.
Fifty percent of adults and 38.4% of children with current asthma had uncontrolled asthma. About 63% of children and 53% of adults with uncontrolled asthma were on long-term asthma control medications. Among children, uncontrolled asthma was significantly associated with being younger than 5 years, having annual household income <$15,000, and reporting cost as barriers to medical care. Among adults, it was significantly associated with being 45 years or older, having annual household income of <$25,000, being "other" race, having less than a 4-year college degree, being a current or former smoker, reporting cost as barriers, being obese, and having chronic obstructive pulmonary disease or depression.
Identifying and targeting modifiable predictors of uncontrolled asthma (low educational attainment, low income, cigarette smoking, and co-morbid conditions including obesity and depression) could improve asthma control.
监测哮喘控制水平对于确定当前治疗的有效性很重要,这可能会降低症状的频率和强度以及功能限制。未控制的哮喘与生活质量下降和医疗保健使用增加有关。本研究的目的是评估当前患有哮喘的人群的哮喘控制水平,并确定相关危险因素。
使用2006年至2010年美国国家健康访问调查(BRFSS)的儿童和成人哮喘回访调查,采用三项损伤指标将哮喘控制分为控制良好或未控制(控制不佳或控制极差):日间症状、夜间症状以及使用短效β2激动剂控制症状。多变量逻辑回归确定了哮喘控制的预测因素。
当前患有哮喘的成年人中有50%以及儿童中有38.4%的哮喘未得到控制。在哮喘未得到控制的儿童中,约63%以及成人中约53%正在使用长期哮喘控制药物。在儿童中,未控制的哮喘与年龄小于5岁、家庭年收入低于15,000美元以及报告费用是医疗保健的障碍显著相关。在成年人中,它与年龄在45岁及以上、家庭年收入低于25,000美元、为“其他”种族、拥有不到四年制大学学位、为当前或既往吸烟者、报告费用是障碍、肥胖以及患有慢性阻塞性肺疾病或抑郁症显著相关。
识别并针对未控制哮喘的可改变预测因素(低教育程度、低收入、吸烟以及包括肥胖和抑郁症在内的合并症)可以改善哮喘控制。