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子宫动脉栓塞术期间的辐射暴露:将患者剂量降至最低的有效措施。

Radiation exposure during uterine artery embolization: effective measures to minimize dose to the patient.

作者信息

Scheurig-Muenkler Christian, Powerski Maciej J, Mueller Johann-Christoph, Kroencke Thomas J

机构信息

Department of Diagnostic and Interventional Radiology, Charité Universitaetsmedizin Berlin, Augustenburger Platz 1, 13353, Berlin, Germany,

出版信息

Cardiovasc Intervent Radiol. 2015 Jun;38(3):613-22. doi: 10.1007/s00270-014-0962-6. Epub 2014 Aug 23.

Abstract

PURPOSE

Evaluation of patient radiation exposure during uterine artery embolization (UAE) and literature review to identify techniques minimizing required dose.

METHODS

A total of 224 of all included 286 (78 %) women underwent UAE according to a standard UAE-protocol (bilateral UAE from unilateral approach using a Rösch inferior mesenteric and a microcatheter, no aortography, no ovarian artery catheterization or embolization) and were analyzed for radiation exposure. Treatment was performed on three different generations of angiography systems: (I) new generation flat-panel detector (N = 108/151); (II) classical image amplifier and pulsed fluoroscopy (N = 79/98); (III) classical image amplifier and continuous fluoroscopy (N = 37/37). Fluoroscopy time (FT) and dose-area product (DAP) were documented. Whenever possible, the following dose-saving measures were applied: optimized source-object, source-image, and object-image distances, pulsed fluoroscopy, angiographic runs in posterior-anterior direction with 0.5 frames per second, no magnification, tight collimation, no additional aortography.

RESULTS

In a standard bilateral UAE, the use of the new generation flat-panel detector in group I led to a significantly lower DAP of 3,156 cGy × cm(2) (544-45,980) compared with 4,000 cGy × cm(2) (1,400-13,000) in group II (P = 0.033). Both doses were significantly lower than those of group III with 8,547 cGy × cm(2) (3,324-35,729; P < 0.001). Other reasons for dose escalation were longer FT due to difficult anatomy or a large leiomyoma load, additional angiographic runs, supplementary ovarian artery embolization, and obesity.

CONCLUSIONS

The use of modern angiographic units with flat panel detectors and strict application of methods of radiation reduction lead to a significantly lower radiation exposure. Target DAP for UAE should be kept below 5,000 cGy × cm(2).

摘要

目的

评估子宫动脉栓塞术(UAE)期间患者的辐射暴露情况,并进行文献综述以确定可将所需剂量降至最低的技术。

方法

在纳入的286名女性中,共有224名(78%)按照标准UAE方案接受了UAE治疗(采用Rösch肠系膜下动脉和微导管从单侧途径进行双侧UAE,不进行主动脉造影,不进行卵巢动脉插管或栓塞),并对其辐射暴露情况进行了分析。治疗在三代不同的血管造影系统上进行:(I)新一代平板探测器(N = 108/151);(II)经典影像增强器和脉冲透视(N = 79/98);(III)经典影像增强器和连续透视(N = 37/37)。记录透视时间(FT)和剂量面积乘积(DAP)。只要有可能,就采用以下剂量节省措施:优化源-物体、源-图像和物体-图像距离,脉冲透视,前后方向的血管造影运行,每秒0.5帧,不放大,严格准直,不进行额外的主动脉造影。

结果

在标准双侧UAE中,I组使用新一代平板探测器导致DAP显著降低,为3156 cGy×cm²(544 - 45980),而II组为4000 cGy×cm²(1400 - 13000)(P = 0.033)。这两个剂量均显著低于III组的8547 cGy×cm²(3324 - (此处原文有误,应为35729)35729;P < 0.001)。剂量增加的其他原因包括解剖结构复杂或平滑肌瘤负荷大导致FT延长、额外的血管造影运行、补充性卵巢动脉栓塞和肥胖。

结论

使用带有平板探测器 的现代血管造影设备并严格应用辐射减少方法可显著降低辐射暴露。UAE的目标DAP应保持在5000 cGy×cm²以下。

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