Van Bever Elien, Elseviers Monique, Plovie Marijke, Vandeputte Lieselot, Van Bortel Luc, Vander Stichele Robert
Heymans Institute of Pharmacology, Ghent University, Ghent, Belgium.
Basic Clin Pharmacol Toxicol. 2015 Mar;116(3):264-72. doi: 10.1111/bcpt.12314. Epub 2014 Oct 9.
International Non-proprietary Name (INN) prescribing is the use of the name of the active ingredient(s) instead of the brand name for prescribing. In Belgium, INN prescribing began in 2005 and a major policy change occurred in 2012. The aim was to explore the opinions of Dutch-speaking general practitioners (GPs) and pharmacists. An electronic questionnaire with 39 five-point Likert scale statements and one open question was administered in 2013. Multivariate analysis was performed with multiple linear regression on a sum score for benefit statements and for drawback statements. Answers to the open question were qualitatively analysed. We received 745 valid responses with a representable sample for both subgroups. Participants perceived the motives to introduce INN prescribing as purely economic (to reduce pharmaceutical expenditures for the government and the patient). Participants accepted the concept of INN prescribing, but 88% stressed the importance of guaranteed treatment continuity, especially in older, chronic patients, to prevent patient confusion, medication non-adherence and erroneous drug use. In conclusion, the current way in which INN prescribing is applied in Belgium leads to many concerns among primary health professionals about patient confusion and medication adherence. Slightly adapting the current concept of INN prescribing to these concerns can turn INN prescribing into one of the major policies in Belgium to reduce pharmaceutical expenditures and to stimulate rational drug prescribing.
国际非专利名称(INN)处方是指在开处方时使用活性成分的名称而非品牌名称。在比利时,INN处方于2005年开始实施,2012年发生了一项重大政策变化。目的是探讨荷兰语区全科医生(GP)和药剂师的意见。2013年发放了一份包含39条五点李克特量表陈述和一个开放式问题的电子问卷。对益处陈述和缺点陈述的总分进行多元线性回归多变量分析。对开放式问题的答案进行定性分析。我们收到了745份有效回复,两个亚组的样本均具有代表性。参与者认为引入INN处方的动机纯粹是经济性的(为政府和患者降低药品支出)。参与者接受INN处方的概念,但88%的人强调保证治疗连续性的重要性,尤其是在老年慢性病患者中,以防止患者混淆、用药依从性差和错误用药。总之,比利时目前应用INN处方的方式引起了基层医疗专业人员对患者混淆和用药依从性的诸多担忧。根据这些担忧对当前INN处方概念稍作调整,可使INN处方成为比利时降低药品支出和促进合理用药的主要政策之一。