东低地大猩猩（Gorilla beringei graueri）的完整线粒体基因组及大猩猩物种的线粒体基因组比较研究
The complete mitochondrial genome of eastern lowland gorilla, Gorilla beringei graueri, and comparative mitochondrial genomics of Gorilla species.
作者信息
Hu Xiao-di, Gao Li-zhi
机构信息
a Faculty of Life Science and Technology , Kunming University of Science and Technology , Kunming , China and.
b Plant Germplasm and Genomics Center, Germplasm Bank of Wild Species in Southwest China, Kunming Institute of Botany, Chinese Academy of Sciences , Kunming , China.
出版信息
Mitochondrial DNA A DNA Mapp Seq Anal. 2016;27(2):1484-5. doi: 10.3109/19401736.2014.953103. Epub 2014 Aug 27.
In this study, we determined the complete mitochondrial (mt) genome of eastern lowland gorilla, Gorilla beringei graueri for the first time. The total genome was 16,416 bp in length. It contained a total of 13 protein-coding genes, 22 transfer RNA genes, 2 ribosomal RNA genes and 1 control region (D-loop region). The base composition was A (30.88%), G (13.10%), C (30.89%) and T (25.13%), indicating that the percentage of A+T (56.01%) was higher than G+C (43.99%). Comparisons with the other publicly available Gorilla mitogenome showed the conservation of gene order and base compositions but a bunch of nucleotide diversity. This complete mitochondrial genome sequence will provide valuable genetic information for further studies on conservation genetics of eastern lowland gorilla.
在本研究中，我们首次测定了东部低地大猩猩（Gorilla beringei graueri）的完整线粒体（mt）基因组。该基因组全长16,416 bp。它总共包含13个蛋白质编码基因、22个转运RNA基因、2个核糖体RNA基因和1个控制区（D环区）。碱基组成为A（30.88%）、G（13.10%）、C（30.89%）和T（25.13%），表明A+T的百分比（56.01%）高于G+C（43.99%）。与其他公开的大猩猩线粒体基因组进行比较，结果显示基因顺序和碱基组成具有保守性，但存在大量核苷酸多样性。这个完整的线粒体基因组序列将为东部低地大猩猩保护遗传学的进一步研究提供有价值的遗传信息。
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