Jimenez de León J, Luz Picazo M, Mora M, Fiter L, Cisneros J, Burgos E, de la Peña J, López P, Martínez-Piñeiro J A
Arch Esp Urol. 1989 Nov-Dec;42(9):931-5.
We report on a female patient who presented with urethrorrhagia and a palpable urethral mass which was diagnosed as urethral diverticulum, the site of a tumor that proved to be adenocarcinoma of the urethra. The patient underwent radical urethrectomy and pelvic and inguinal lymphadenectomy. Urethral reconstruction was performed using a vesical flap following the technique described by Tanagho. Thereafter, she received 6 courses of M-VAC polychemotherapy. Diverticulum and carcinoma of the female urethra are uncommon. Adenocarcinoma is the most common tumor type encountered in these diverticula. Diagnosis is clinically simple and treatment is by radical surgery and radiotherapy. The foregoing treatment modalities have improved patient survival when the tumor is detected early. This tumor type is particularly aggressive and outcome depends on tumor stage.
我们报告了一名女性患者,她出现尿道出血,可触及尿道肿物,诊断为尿道憩室,该部位的肿瘤经证实为尿道腺癌。患者接受了根治性尿道切除术以及盆腔和腹股沟淋巴结清扫术。按照Tanagho描述的技术,使用膀胱瓣进行尿道重建。此后,她接受了6个疗程的M-VAC联合化疗。女性尿道憩室和癌并不常见。腺癌是这些憩室中最常见的肿瘤类型。诊断在临床上较为简单,治疗方法为根治性手术和放疗。当肿瘤早期被检测到时,上述治疗方式可提高患者生存率。这种肿瘤类型具有特别强的侵袭性,预后取决于肿瘤分期。