Jaber S, De Jong A, Castagnoli A, Futier E, Chanques G
Inserm U1046, intensive care unit, anesthesia and critical care department B, Saint-Éloi teaching hospital, université Montpellier 1, centre hospitalier universitaire Montpellier, 80, avenue Augustin Fliche, 34295 Montpellier cedex 5, France.
Inserm U1046, intensive care unit, anesthesia and critical care department B, Saint-Éloi teaching hospital, université Montpellier 1, centre hospitalier universitaire Montpellier, 80, avenue Augustin Fliche, 34295 Montpellier cedex 5, France.
Ann Fr Anesth Reanim. 2014 Jul-Aug;33(7-8):487-91. doi: 10.1016/j.annfar.2014.07.742. Epub 2014 Aug 29.
After surgery, hypoxemia and/or acute respiratory failure (ARF) mainly develop following abdominal and/or thoracic surgery. Anesthesia, postoperative pain and surgery will induce respiratory modifications: hypoxemia, pulmonary volumes decrease and atelectasis associated to a restrictif syndrome and a diaphragm dysfunction. Maintenance of adequate oxygenation in the postoperative period is of major importance, especially when pulmonary complications such as ARF occur. Although invasive endotracheal mechanical ventilation has remained the cornerstone of ventilatory strategy for many years for severe acute respiratory failure, several studies have shown that mortality associated with pulmonary disease is largely related to complications of postoperative reintubation and mechanical ventilation. Therefore, major objectives for anesthesiologists and surgeons are first to prevent the occurrence of postoperative complications and second if ARF occurs is to ensure oxygen administration and carbon dioxide CO2 removal while avoiding intubation. Non-invasive ventilation (NIV) does not require endotracheal tube or tracheotomy and its use is well established to prevent ARF occurrence (prophylactic treatment) or to treat ARF to avoid reintubation (curative treatment). Studies shows that patient-related risk factors, such as chronic obstructive pulmonary disease (COPD), age older than 60 years, American Society of Anesthesiologists ASA class of II or higher, obesity, functional dependence, and congestive heart failure, increase the risk for postoperative pulmonary complications. Rationale for postoperative NIV use is the same as the post-extubation NIV use plus the specificities due to the respiratory modifications induced by the surgery and anesthesia. Postoperative NIV improves gas exchange, decreases work of breathing and reduces atelectasis. The aims of this article are (1) to review the main respiratory modifications induced by surgery and anesthesia which justify postoperative NIV use (2) to offer some recommendations to apply safely postoperative NIV and (3) to present the main results obtained with preventive and curative NIV in a surgical context.
手术后,低氧血症和/或急性呼吸衰竭(ARF)主要发生在腹部和/或胸部手术后。麻醉、术后疼痛和手术会引起呼吸改变:低氧血症、肺容量减少以及与限制性综合征和膈肌功能障碍相关的肺不张。术后维持充足的氧合至关重要,尤其是在发生诸如ARF等肺部并发症时。尽管多年来有创气管内机械通气一直是严重急性呼吸衰竭通气策略的基石,但多项研究表明,与肺部疾病相关的死亡率在很大程度上与术后再次插管和机械通气的并发症有关。因此,麻醉医生和外科医生的主要目标首先是预防术后并发症的发生,其次是如果发生ARF,要确保给氧和排出二氧化碳,同时避免插管。无创通气(NIV)不需要气管内插管或气管切开术,其用于预防ARF发生(预防性治疗)或治疗ARF以避免再次插管(治疗性治疗)已得到充分确立。研究表明,与患者相关的危险因素,如慢性阻塞性肺疾病(COPD)、年龄大于60岁、美国麻醉医师协会(ASA)分级为II级或更高、肥胖、功能依赖和充血性心力衰竭,会增加术后肺部并发症的风险。术后使用NIV的基本原理与拔管后使用NIV相同,再加上手术和麻醉引起的呼吸改变所具有的特殊性。术后NIV可改善气体交换、减少呼吸功并减少肺不张。本文的目的是:(1)回顾由手术和麻醉引起的主要呼吸改变,这些改变证明术后使用NIV是合理的;(2)提供一些安全应用术后NIV的建议;(3)介绍在手术背景下预防性和治疗性NIV所取得的主要结果。