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大鼠小脑小球的三维重建与突触结构

Three-dimensional reconstruction and synaptic architecture of cerebellar glomeruli in the rat.

作者信息

Jakab R L

机构信息

Neurobiology Res. Lab. of the Hungarian Academy of Sciences, Budapest.

出版信息

Acta Morphol Hung. 1989;37(1-2):11-20.

PMID:2518341
Abstract

Cerebellar glomeruli of simple type were studied by quantitative morphological and stereological methods. It has been found that in one glomerulus the centrally located mossy terminal forms synaptic contacts with about 50 granule cell dendrites, all deriving from distinct granule cells. The three-dimensional reconstruction of the glomeruli revealed that the terminal portion of the dendrites, the so called digits, are elongated, thin processes. Synaptic contacts by mossy terminals are established exclusively on the dendritic digits. Although these digits are the main postsynaptic targets for the Golgi axon terminals as well, these inhibitory endings might also synapse with the proximal portion of the granule cell dendrites.

摘要

采用定量形态学和体视学方法研究了简单型小脑小球。研究发现,在一个小球中,位于中央的苔藓状终末与约50个颗粒细胞树突形成突触联系,这些树突均来自不同的颗粒细胞。小球的三维重建显示,树突的终末部分,即所谓的指状突起,是细长的薄突起。苔藓状终末的突触联系仅在树突指状突起上建立。尽管这些指状突起也是高尔基轴突终末的主要突触后靶点,但这些抑制性终末也可能与颗粒细胞树突的近端形成突触。

相似文献

1
Three-dimensional reconstruction and synaptic architecture of cerebellar glomeruli in the rat.大鼠小脑小球的三维重建与突触结构
Acta Morphol Hung. 1989;37(1-2):11-20.
2
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[Synapses with a different synaptic contact structure in the cerebellar cortex].[小脑皮质中具有不同突触接触结构的突触]
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引用本文的文献

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Ultrastructural contributions to desensitization at cerebellar mossy fiber to granule cell synapses.小脑苔藓纤维至颗粒细胞突触脱敏的超微结构研究
J Neurosci. 2003 Mar 15;23(6):2182-92. doi: 10.1523/JNEUROSCI.23-06-02182.2003.
2
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J Neurosci. 1999 Nov 1;19(21):9663-73. doi: 10.1523/JNEUROSCI.19-21-09663.1999.