Pauls Rachel N, Crisp Catrina C, Novicki Kathleen, Fellner Angela N, Kleeman Steven D
From the *Division of Urogynecology and Reconstructive Pelvic Surgery, TriHealth Good Samaritan Hospital, †Center for Pelvic Floor and Core Rehabilitation, and ‡Hatton Institute for Research and Education, TriHealth, Cincinnati, OH.
Female Pelvic Med Reconstr Surg. 2014 Nov-Dec;20(6):334-41. doi: 10.1097/SPV.0000000000000090.
Pelvic floor physical therapy (PFPT) is often used as a treatment of pelvic floor disorders and may improve function after pelvic reconstructive surgery. However, the long-term impact of this modality is not understood.
This randomized controlled trial compared PFPT to the standard care in women undergoing vaginal reconstruction. The intervention group received PFPT biweekly until 12 weeks postoperatively, in conjunction with a physician assessment. Control subjects underwent a physician assessment alone at all postoperative intervals. The final follow-up was at 24 weeks. Physical examinations (pelvic organ prolapse quantification assessment), intravaginal electromyography, voiding diaries, and validated questionnaires were completed by all subjects. The primary outcome was change in the World Health Organization Quality of Life-BREF.
Forty-nine women completed the study, 24 in the PFPT group and 25 in the control group. Although electromyography measures showed better muscular function in PFPT subjects after 12 weeks, at 6 months after surgery, this was no longer noted. However, quality of life parameters improved for the entire sample at 24 weeks, with no difference between groups. Positive change from 12 to 24 weeks was also documented in scores on the Pelvic Floor Distress Inventory-20 (P = 0.04) and Pelvic Floor Impact Questionnaire-7 (P = 0.018), corresponding with continued improvement in bladder symptoms. Finally, Prolapse and Incontinence Sexual Questionnaire-12 and Female Sexual Function Index scores improved between 12 and 24 weeks, suggesting better sexual function overall with time elapsed from surgery.
Quality of life improves in all subjects after vaginal reconstructive surgery, with ongoing benefit between 3 and 6 months. Nevertheless, standardized PFPT was not associated with differences at 24 weeks in this cohort of women.
盆底物理治疗(PFPT)常被用于治疗盆底功能障碍,且可能改善盆腔重建术后的功能。然而,这种治疗方式的长期影响尚不清楚。
本随机对照试验将PFPT与接受阴道重建手术的女性的标准护理进行了比较。干预组每两周接受一次PFPT治疗,直至术后12周,并结合医生评估。对照组仅在所有术后随访时接受医生评估。最终随访时间为24周。所有受试者均完成了体格检查(盆腔器官脱垂定量评估)、阴道内肌电图检查、排尿日记以及经过验证的问卷调查。主要结局指标为世界卫生组织生活质量简表(WHOQOL-BREF)的变化。
49名女性完成了研究,PFPT组24名,对照组25名。尽管肌电图测量显示PFPT组受试者在12周后肌肉功能更好,但在术后6个月时,这种情况已不再明显。然而,整个样本在24周时生活质量参数有所改善,两组之间无差异。盆底困扰量表-20(PFDI-20)(P = 0.04)和盆底影响问卷-7(PFIQ-7)(P = 0.018)的评分在12至24周之间也有正向变化,这与膀胱症状的持续改善相对应。最后,脱垂与尿失禁性功能问卷-12(PISQ-12)和女性性功能指数(FSFI)评分在12至24周之间有所改善,表明随着手术时间的推移,总体性功能有所改善。
阴道重建术后所有受试者的生活质量均有所改善,在3至6个月期间持续受益。然而,在这组女性中,标准化的PFPT在24周时并未显示出差异。