Nickel Barbara, McClure Timothy, Moriarty John
US Teleradiology and Quantum Medical Radiology Group, 500 W. Arenas Rd. #8, Palm Springs, CA, 92262, USA,
Cardiovasc Intervent Radiol. 2015 Aug;38(4):1021-4. doi: 10.1007/s00270-014-0986-y. Epub 2014 Sep 5.
Venous thromboembolic disease is a significant cause of morbidity and mortality, particularly in the setting of large volume pulmonary embolism. Thrombolytic therapy has been shown to be a successful treatment modality; however, its use somewhat limited due to the risk of hemorrhage and potential for distal embolization in the setting of large mobile thrombi. In patients where either thrombolysis is contraindicated or unsuccessful, and conventional therapies prove inadequate, surgical thrombectomy may be considered. We present a case of percutaneous endovascular extraction of a large mobile mass extending from the inferior vena cava into the right atrium using the Angiovac device, a venovenous bypass system designed for high-volume aspiration of undesired endovascular material. Standard endovascular methods for removal of cancer-associated thrombus, such as catheter-directed lysis, maceration, and exclusion, may prove inadequate in the setting of underlying tumor thrombus. Where conventional endovascular methods either fail or are unsuitable, endovascular thrombectomy with the Angiovac device may be a useful and safe minimally invasive alternative to open resection.
静脉血栓栓塞性疾病是发病和死亡的重要原因,尤其是在大面积肺栓塞的情况下。溶栓治疗已被证明是一种成功的治疗方式;然而,由于出血风险以及在存在大型可移动血栓的情况下发生远端栓塞的可能性,其应用受到一定限制。在溶栓治疗禁忌或不成功且传统治疗方法证明不足的患者中,可考虑手术取栓。我们报告一例使用Angiovac装置经皮血管内取出从下腔静脉延伸至右心房的大型可移动肿块的病例,Angiovac装置是一种静脉 - 静脉旁路系统,设计用于大量抽吸不需要的血管内物质。用于清除癌症相关血栓的标准血管内方法,如导管定向溶栓、碎栓和封堵,在存在潜在肿瘤血栓的情况下可能证明不足。当传统血管内方法失败或不合适时,使用Angiovac装置进行血管内取栓可能是一种有用且安全的微创替代开放切除术的方法。