Suppr超能文献

评“局部非渗透阴离子决定神经元氯离子浓度”一文。

Comment on "Local impermeant anions establish the neuronal chloride concentration".

机构信息

Department of Biosciences, University of Helsinki, Helsinki, Finland.

Department of Physiology and Biophysics, Case Western Reserve University School of Medicine, Cleveland, OH, USA.

出版信息

Science. 2014 Sep 5;345(6201):1130. doi: 10.1126/science.1252978.

Abstract

Glykys et al. (Reports, 7 February 2014, p. 670) conclude that, rather than ion transporters, "local impermeant anions establish the neuronal chloride concentration" and thereby determine "the magnitude and direction of GABAAR currents at individual synapses." If this were possible, perpetual ion-motion machines could be constructed. The authors' conclusions conflict with basic thermodynamic principles.

摘要

格利克斯等人(报告,2014 年 2 月 7 日,第 670 页)得出结论,不是离子转运体,“局部不可渗透的阴离子决定神经元氯离子浓度”,从而决定“单个突触 GABAAR 电流的幅度和方向”。如果这是可能的,那么就可以构建永久性的离子运动机器。作者的结论与基本热力学原理相冲突。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验