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臂丛神经损伤治疗的最新进展

Recent advances in the management of brachial plexus injuries.

作者信息

Bhandari Prem Singh, Maurya Sanjay

机构信息

Department of Plastic Surgery, Command Hospital (NC), Panchkula, Haryana, India.

Command Hospital (WC), Chandimandir Cantt, Panchkula, Haryana, India.

出版信息

Indian J Plast Surg. 2014 May;47(2):191-8. doi: 10.4103/0970-0358.138941.

Abstract

Management of brachial plexus injury is a demanding field of hand and upper extremity surgery. With currently available microsurgical techniques, functional gains are rewarding in upper plexus injuries. However, treatment options in the management of flail and anaesthetic limb are still evolving. Last three decades have witnessed significant developments in the management of these injuries, which include a better understanding of the anatomy, advances in the diagnostic modalities, incorporation of intra-operative nerve stimulation techniques, more liberal use of nerve grafts in bridging nerve gaps, and the addition of new nerve transfers, which selectively neurotise the target muscles close to the motor end plates. Newer research works on the use of nerve allografts and immune modulators (FK 506) are under evaluation in further improving the results in nerve reconstruction. Direct reimplantation of avulsed spinal nerve roots into the spinal cord is another area of research in brachial plexus reconstruction.

摘要

臂丛神经损伤的治疗是手部和上肢外科中一个具有挑战性的领域。运用目前可用的显微外科技术,对上臂丛神经损伤进行功能恢复是值得的。然而,连枷臂和麻醉肢体的治疗方案仍在不断发展。在过去三十年中,这些损伤的治疗取得了重大进展,包括对解剖结构有了更深入的了解、诊断方式的进步、术中神经刺激技术的应用、在桥接神经缺损时更广泛地使用神经移植物,以及增加了新的神经移位术,这些技术可选择性地使靠近运动终板的目标肌肉神经化。关于使用同种异体神经移植物和免疫调节剂(FK 506)的最新研究正在评估中,以进一步改善神经重建的效果。将撕脱的脊神经根直接重新植入脊髓是臂丛神经重建的另一个研究领域。

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