一名再生障碍性贫血患者合并阵发性睡眠性血红蛋白尿克隆，反复出现危及生命的血小板输注反应。
Recurrent life-threatening reactions to platelet transfusion in an aplastic anaemia patient with a paroxysmal nocturnal haemoglobinuria clone.
作者信息
Mohamed M, Bates G, Richardson D, Burrows L
机构信息
Haematology Department, Launceston General Hospital, Launceston, Tasmania, Australia; Launceston Clinical School, University of Tasmania, Launceston, Tasmania, Australia.
出版信息
Intern Med J. 2014 Sep;44(9):925-7. doi: 10.1111/imj.12528.
A 60-year-old woman was diagnosed with non-severe aplastic anaemia when she presented with anaemia and thrombocytopenia. She developed recurrent life-threatening hypotensive reactions during transfusion of leukodepleted platelet concentrates, and washed platelet concentrates prevented the development of such reactions subsequently. A paroxysmal nocturnal haemoglobinuria clone was detected on investigating for aplastic anaemia, which has been speculated to play a role in the recurrent hypotensive reactions.
一名60岁女性因贫血和血小板减少被诊断为非重型再生障碍性贫血。她在输注去白细胞血小板浓缩物期间反复出现危及生命的低血压反应，而输注洗涤血小板浓缩物随后防止了此类反应的发生。在对再生障碍性贫血进行调查时检测到阵发性夜间血红蛋白尿克隆，推测其在反复出现的低血压反应中起作用。
Zotero 插件