Groth John V, Prabhu Sanjiv, Wiley Elizabeth
University of Illinois Hospital & Health Sciences System, Chicago, IL.
Appl Immunohistochem Mol Morphol. 2016 Feb;24(2):144-8. doi: 10.1097/PAI.0000000000000066.
The presence of benign epithelial inclusions in axillary lymph nodes coexistant with breast disease is a rare event; however, their presence makes the assessment of nodal disease diagnostically challenging. Broadly, these inclusions can be classified as glandular (müllerian type or nonmüllerian type), mixed glandular-squamous, and squamous. Among these the presence of benign müllerian-type glandular inclusions with concurrent breast parenchymal disease is an exceedingly rare event, with 10 previous cases reported in the literature, 2 coexisting with infiltrating ductal-type mammary carcinoma in axillary lymph nodes. Here, we report the first case of coexistent invasive lobular carcinoma and endosalpingiosis in an axillary lymph node.
腋窝淋巴结中良性上皮性包涵体与乳腺疾病共存是一种罕见情况;然而,它们的存在使得对淋巴结疾病的评估在诊断上具有挑战性。广义上,这些包涵体可分为腺性(苗勒氏型或非苗勒氏型)、腺性 - 鳞状混合性和鳞状。其中,良性苗勒氏型腺性包涵体与乳腺实质疾病同时存在是极为罕见的情况,文献中此前报道过10例,其中2例在腋窝淋巴结中与浸润性导管型乳腺癌共存。在此,我们报告首例腋窝淋巴结中浸润性小叶癌与输卵管内膜异位症共存的病例。