Reser Diana, Hemelrijck Mathias van, Pavicevic Jovana, Tolboom Herman, Holubec Tomas, Falk Volkmar, Jacobs Stephan
Department of Cardiovascular Surgery, University Hospital Zurich, Zurich, Switzerland.
University of Zurich, Zurich, Switzerland.
Thorac Cardiovasc Surg. 2015 Jun;63(4):313-8. doi: 10.1055/s-0034-1389085. Epub 2014 Sep 10.
Minimally invasive direct coronary artery bypass grafting (MIDCAB) has gained wide acceptance for the treatment of single vessel disease of the left anterior descending artery (LAD). Here, we present our single center experience of 152 consecutive patients.
All patients underwent MIDCAB through a left anterior minithoracotomy between January 1, 2009, and December 31, 2012. Preoperative, intraoperative, postoperative, and follow-up data including major adverse cardiac and cerebrovascular events (MACCE) and need for re-intervention were collected.
Mean age was 64.4 ± 11 years, median additive EuroSCORE 3 (0-11), 84% were male. All except one patient were successfully operated without cardiopulmonary bypass. Seven patients with unexpected severely calcified LADs were converted to sternotomy (4.6%); 91.3% were extubated in the operating room or on the day of surgery. Median stay at the intensive care unit and in hospital were 1 (0-97) and 7 (1-49) days, respectively. Thirty-day mortality was 1.9%. There was no stroke. Five patients (3.2%) had to be re-explored for bleeding and 95% received no transfusion. Median follow-up was 24 months (0-97) and complete in 93.3% with overall survival of 92.4 ± 0.2% and MACCE-free survival of 96.1 ± 1.7%. Two patients had a re-intervention of the LAD.
MIDCAB is a safe procedure with low postoperative morbidity, mortality, and favorable mid-term MACCE-free survival in selected patients that should be discussed in a heart team setting to evaluate the "ideal" individual treatment option.
微创直接冠状动脉旁路移植术(MIDCAB)已被广泛应用于治疗左前降支(LAD)单支血管病变。在此,我们介绍我们单中心连续152例患者的经验。
2009年1月1日至2012年12月31日期间,所有患者均通过左前小切口行MIDCAB。收集术前、术中和术后以及随访数据,包括主要不良心脑血管事件(MACCE)和再次干预的需求。
平均年龄为64.4±11岁,欧洲心脏手术风险评估系统(EuroSCORE)中位数为3(0 - 11),84%为男性。除1例患者外,所有患者均在非体外循环下成功完成手术。7例LAD意外严重钙化的患者转为胸骨正中切开术(4.6%);91.3%的患者在手术室或手术当天拔管。在重症监护病房和住院的中位时间分别为1(0 - 97)天和7(1 - 49)天。30天死亡率为1.9%。无卒中发生。5例患者(3.2%)因出血需再次手术,95%的患者未接受输血。中位随访时间为24个月(0 - 97),93.3%的患者随访完整,总体生存率为92.4±0.2%,无MACCE生存率为96.1±1.7%。2例患者对LAD进行了再次干预。
MIDCAB是一种安全的手术方法,术后发病率、死亡率低,在特定患者中具有良好的中期无MACCE生存率,应在心脏团队环境中进行讨论,以评估“理想”的个体化治疗方案。