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在一名患有肝素诱导的血小板减少症和血栓形成的患者中成功植入左心室辅助装置。

Successful implantation of a left ventricular assist device in a patient with heparin-induced thrombocytopenia and thrombosis.

作者信息

Garland Cassandra, Somogyi David

出版信息

J Extra Corpor Technol. 2014 Jun;46(2):162-5.

Abstract

We report the case of a 27-year-old woman with signs of heparin-induced thrombocytopenia and thrombosis (HITT) and left heart failure presenting for urgent implantation of a left ventricular assist device (LVAD). HITT can occur in 4.2-6.1% of patients with LVADs. If the patient remains hemodynamically stable, implantation can be delayed for several months until the heparin/PF-4 antibodies decline allowing the use of heparin on cardiopulmonary bypass, However, in most cases related to cardiogenic shock, surgery cannot be delayed. We present the case of a patient who underwent implantation of a HeartMate II LVAD and discuss management strategy using bivalirudin during cardiopulmonary bypass.

摘要

我们报告了一名27岁女性的病例,该患者有肝素诱导的血小板减少症和血栓形成(HITT)的体征以及左心衰竭,前来紧急植入左心室辅助装置(LVAD)。LVAD患者中4.2%-6.1%会发生HITT。如果患者血流动力学保持稳定,植入可推迟数月,直到肝素/PF-4抗体下降,以便在体外循环时使用肝素。然而,在大多数与心源性休克相关的病例中,手术不能推迟。我们介绍了一名接受HeartMate II LVAD植入的患者的病例,并讨论了在体外循环期间使用比伐卢定的管理策略。

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