Garland Cassandra, Somogyi David
J Extra Corpor Technol. 2014 Jun;46(2):162-5.
We report the case of a 27-year-old woman with signs of heparin-induced thrombocytopenia and thrombosis (HITT) and left heart failure presenting for urgent implantation of a left ventricular assist device (LVAD). HITT can occur in 4.2-6.1% of patients with LVADs. If the patient remains hemodynamically stable, implantation can be delayed for several months until the heparin/PF-4 antibodies decline allowing the use of heparin on cardiopulmonary bypass, However, in most cases related to cardiogenic shock, surgery cannot be delayed. We present the case of a patient who underwent implantation of a HeartMate II LVAD and discuss management strategy using bivalirudin during cardiopulmonary bypass.
我们报告了一名27岁女性的病例,该患者有肝素诱导的血小板减少症和血栓形成(HITT)的体征以及左心衰竭,前来紧急植入左心室辅助装置(LVAD)。LVAD患者中4.2%-6.1%会发生HITT。如果患者血流动力学保持稳定,植入可推迟数月,直到肝素/PF-4抗体下降,以便在体外循环时使用肝素。然而,在大多数与心源性休克相关的病例中,手术不能推迟。我们介绍了一名接受HeartMate II LVAD植入的患者的病例,并讨论了在体外循环期间使用比伐卢定的管理策略。