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循环性死亡后捐赠器官用于肺移植的获取:阿尔弗雷德技术。

Procurement of lungs for transplantation following donation after circulatory death: the Alfred technique.

作者信息

Saxena Pankaj, Zimmet Adam D, Snell Greg, Levvey Bronwyn, Marasco Silvana F, McGiffin David C

机构信息

Department of Cardiothoracic Surgery, The Alfred Hospital and Monash University, Melbourne, Australia.

Department of Cardiothoracic Surgery, The Alfred Hospital and Monash University, Melbourne, Australia.

出版信息

J Surg Res. 2014 Dec;192(2):642-6. doi: 10.1016/j.jss.2014.07.063. Epub 2014 Aug 4.

DOI:10.1016/j.jss.2014.07.063
PMID:25217512
Abstract

INTRODUCTION

Donation after circulatory death (DCD) is an evolving method for lung transplantation (LTx) with results comparable to donation after brain death (DBD).

MATERIALS AND METHODS

DCD lung transplant program requires a systematic approach for an efficient utilization of hospital resources. The surgical techniques have been developed to minimize the ischemic time during lung procurement. We have presented our management protocol and the surgical techniques as used at the Alfred Hospital in Melbourne, Australia.

RESULTS

We have transplanted 92 recipients with lungs procured from 91 donors over an 8 year period from May 2006 to July 2014. This accounted for an extra 19% lung transplant operations performed during this time period. Operative mortality was 1% and 8 year survival was 71% in DCD lung recipients.

CONCLUSIONS

DCD lung transplantation provides an additional significant pool of lung donors with satisfactory short and long term outcomes.

摘要

引言

心脏死亡后器官捐献(DCD)是一种不断发展的肺移植(LTx)方法,其结果与脑死亡后器官捐献(DBD)相当。

材料与方法

DCD肺移植项目需要一种系统的方法来有效利用医院资源。已开发出手术技术以尽量减少肺获取过程中的缺血时间。我们展示了澳大利亚墨尔本阿尔弗雷德医院所采用的管理方案和手术技术。

结果

在2006年5月至2014年7月的8年期间,我们为92名受者移植了来自91名供者的肺。这占该时间段内额外进行的19%的肺移植手术。DCD肺移植受者的手术死亡率为1%,8年生存率为71%。

结论

DCD肺移植提供了大量额外的肺供者,其短期和长期结果令人满意。

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