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单纯瓣叶交界脱垂二尖瓣修复术的长期疗效:长达17年的经验

Long-term outcomes of mitral valve repair for isolated commissural prolapse: up to 17-year experience.

作者信息

Shimizu Atsushi, Kasegawa Hitoshi, Tabata Minoru, Fukui Toshihiro, Takanashi Shuichiro

机构信息

Department of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan.

Department of Cardiovascular Surgery, Sakakibara Heart Institute, Tokyo, Japan.

出版信息

Ann Thorac Surg. 2015 Jan;99(1):43-7. doi: 10.1016/j.athoracsur.2014.04.144. Epub 2014 Sep 12.

Abstract

BACKGROUND

Mitral valve repair has been shown to be effective for degenerative mitral regurgitation (MR). However, outcomes of mitral valve repair for commissural prolapse has not been well defined. Commissural prolapse has been often categorized into the groups of posterior leaflet prolapse or bileaflet prolapse, and outcomes and prognosis of isolated commissural prolapse has been rarely reported. We aimed to determine clinical and echocardiographic outcomes of mitral valve repair for isolated commissural lesion.

METHODS

Between 1992 and 2010, 1,112 patients underwent mitral valve repair for degenerative MR at our institution. Among those, we reviewed 122 patients with isolated commissural prolapse. We analyzed operative outcomes, long-term survival rate, freedom from reoperation rate, and freedom from recurrent moderate or severe MR rate.

RESULTS

The mean age was 57.0 ± 14.4 years old, 83 patients (68.0%) were men, 16 patients (13.1%) had infective endocarditis, 43 patients (35.2%) had atrial fibrillation, 27 patients (22.1%) had anterolateral commissural prolapse, 91 (74.6%) had posteromedial commissural prolapse, and 4 (3.3%) had bilateral commissural prolapse. We performed leaflet resection in 111 (91.0%) (concomitant sliding plasty in 43), chordal replacement in 94 (77.0%), and ring annuloplasty in 121 patients (99.2%). Residual mild MR was confirmed in 7 patients (5.7%) on predischarge echocardiography. No patients had moderate or severe MR at the time of discharge. Fifteen-year survival and freedom from mitral reoperation were 87.6% and 93.0%, respectively. Freedom from recurrent moderate or severe MR at 15 years was 87.4%.

CONCLUSIONS

Mitral valve repair for isolated commissural prolapse demonstrated excellent early and late outcomes.

摘要

背景

二尖瓣修复术已被证明对退行性二尖瓣反流(MR)有效。然而,连合部脱垂的二尖瓣修复术的结果尚未得到明确界定。连合部脱垂常被归类为后叶脱垂或双叶脱垂组,孤立性连合部脱垂的结果和预后鲜有报道。我们旨在确定孤立性连合部病变的二尖瓣修复术的临床和超声心动图结果。

方法

1992年至2010年期间,我院1112例患者因退行性MR接受了二尖瓣修复术。其中,我们回顾了122例孤立性连合部脱垂患者。我们分析了手术结果、长期生存率、再次手术率以及无复发性中重度MR率。

结果

平均年龄为57.0±14.4岁,83例(68.0%)为男性,16例(13.1%)有感染性心内膜炎,43例(35.2%)有房颤,27例(22.1%)有前外侧连合部脱垂,91例(74.6%)有后内侧连合部脱垂,4例(3.3%)有双侧连合部脱垂。111例(91.0%)患者进行了瓣叶切除(43例同时进行了滑动成形术),94例(77.0%)患者进行了腱索置换,121例(99.2%)患者进行了瓣环成形术。出院前超声心动图证实7例(5.7%)患者有残余轻度MR。出院时无患者有中重度MR。15年生存率和无二尖瓣再次手术率分别为87.6%和93.0%。15年时无复发性中重度MR率为87.4%。

结论

孤立性连合部脱垂的二尖瓣修复术显示出优异的早期和晚期结果。

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