萘替芬所致变应性接触性皮炎。两例报告。

Allergic contact dermatitis to naftifine. Report of two cases.

作者信息

Senff H, Tholen S, Stieler W, Reinel D, Hausen B M

机构信息

Department of Dermatology, University of Essen, FRG.

出版信息

Dermatologica. 1989;178(2):107-8. doi: 10.1159/000248402.

DOI:10.1159/000248402

PMID:2522401

Abstract

We report on two cases of allergic contact dermatitis due to naftifine, an antimycotic substance. Epicutaneous tests were positive with the reagent itself but not with other compounds of the ointment. Additionally, one of the patients reacted to an ointment containing clotrimazole. Until now, only few cases of contact allergy to naftifine have been described, but an increasing number is expected.

摘要

我们报告了两例因抗真菌药物萘替芬引起的过敏性接触性皮炎病例。斑贴试验显示，患者对试剂本身呈阳性反应，但对软膏中的其他化合物呈阴性反应。此外，其中一名患者对含有克霉唑的软膏也有反应。到目前为止，仅有少数几例萘替芬接触过敏的病例被报道，但预计此类病例数量会不断增加。