Tomczak Hanna, Szałek Edyta, Grześkowiak Edmund
Central Microbiological Laboratory, H. Święcicki Clinical Hospital, University of Medical Sciences, Poznań, Poland.
Clinical Pharmacy and Biopharmacy Department and Unit, University of Medical Sciences, Poznań, Poland.
Postepy Hig Med Dosw (Online). 2014 Aug 29;68:1036-9. doi: 10.5604/17322693.1118989.
Urinary tract infections (UTIs) in women are a growing clinical concern. The most frequent risk factors of UTIs with fungal aetiology in women are: antibiotic therapy (especially broad-spectrum antibiotics), immunosuppressive therapy, diabetes, malnutrition, pregnancy, and frequent intercourse. The aim of the study was to analyse urinary tract infections with Candida spp. aetiology in women hospitalised at the Clinical Hospital in Poznań, Poland, between 2009 and 2011. The investigations revealed that as many as 71% of positive urine cultures with Candida fungi came from women. The following fungi were most frequently isolated from the patients under analysis: C. albicans (47%), C. glabrata (31%), C. tropicalis (6%), C. krusei (3%). In order to diagnose a UTI the diagnosis cannot be based on a single result of a urine culture. Due to the small number of antifungal drugs and high costs of treatment, antifungal drugs should be applied with due consideration and care.
女性尿路感染(UTIs)是一个日益受到临床关注的问题。女性真菌性病因尿路感染最常见的危险因素包括:抗生素治疗(尤其是广谱抗生素)、免疫抑制治疗、糖尿病、营养不良、妊娠以及频繁性交。本研究的目的是分析2009年至2011年期间在波兰波兹南临床医院住院的女性念珠菌属病因的尿路感染情况。调查显示,多达71%的念珠菌真菌尿培养阳性结果来自女性。从分析的患者中最常分离出的真菌如下:白色念珠菌(47%)、光滑念珠菌(31%)、热带念珠菌(6%)、克柔念珠菌(3%)。为了诊断尿路感染,不能仅基于尿培养的单一结果。由于抗真菌药物数量少且治疗成本高,应谨慎考虑并使用抗真菌药物。