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评论:关注PET定量分析

Commentary: an eye on PET quantification.

作者信息

Walker Matthew D, Sossi Vesna

机构信息

Department of Physics and Astronomy, University of British Columbia, Vancouver, BC, V6T 1Z1, Canada,

出版信息

Mol Imaging Biol. 2015 Feb;17(1):1-3. doi: 10.1007/s11307-014-0791-7.

Abstract

Positron emission tomography (PET) is generally considered to be a quantitative imaging modality, allowing assessment of regional differences in radiotracer accumulation and the derivation of quantitative physiological information. Due to the increasing complexity of PET technology, the quantitative accuracy of PET images has to be continually reassessed if PET is to maintain its quantitative reputation. In this commentary, we discuss the results from a recent inter-scanner study in which the quantitative outcome measures from human studies were compared for three different radiotracers. The approach is a useful complement to standard phantom tests such as those prescribed by NEMA, but the resulting data are more difficult to interpret.

摘要

正电子发射断层扫描(PET)通常被认为是一种定量成像方式,可用于评估放射性示踪剂积聚的区域差异并获取定量生理信息。由于PET技术日益复杂,如果PET要保持其定量声誉,就必须不断重新评估PET图像的定量准确性。在本篇本评论中,我们讨论了最近一项扫描仪间研究的结果,该研究比较了三种不同放射性示踪剂在人体研究中的定量结果指标。这种方法是对标准体模测试(如NEMA规定的那些测试)的有益补充,但所得数据更难解释。

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