[雷恩大学医院50例胸腺上皮肿瘤的回顾性分析]
[Retrospective analysis of 50 thymic epithelial tumors in Rennes university hospital].
作者信息
Kerjouan M, Corre R, Léna H, Choukeir N, Chiforeanu D C, de Latour B, Verhoye J-P, Desrues B, Jouneau S
机构信息
Service de pneumologie, hôpital Pontchaillou, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes, France.
Service de pneumologie, hôpital Pontchaillou, CHU de Rennes, 2, rue Henri-Le-Guilloux, 35033 Rennes, France.
出版信息
Rev Mal Respir. 2014 Sep;31(7):591-600. doi: 10.1016/j.rmr.2013.09.015. Epub 2013 Nov 11.
BACKGROUND
Thymic epithelial tumors (TET), including thymomas and thymic carcinomas, are rare and characterized by very different evolutionary patterns depending on histology and invasion stage. The therapeutic management is not well defined but is a subject of increasing interest. The descriptive and analytic objectives of this retrospective monocentric study were to analyze the clinical characteristics of patients with TET, and to assess the management of these tumors in our centre.
METHODS
Adult patients with TET managed in the Rennes university hospital in the period 2000-2011 were selected via the pathology department. Their clinical and pathological features and survival were analyzed retrospectively.
RESULTS
Fifty TET were retrieved (46 thymomas and 4 thymic carcinomas). Their clinical and histological features and their invasion stages were concordant with published studies. Their diagnostic and therapeutic managements were also in accordance with current guidelines. In univariate analysis, myasthenia and surgery were associated with better survival rates.
CONCLUSION
Management of TET in Rennes university hospital is in accordance with guidelines.
背景
胸腺上皮肿瘤（TET），包括胸腺瘤和胸腺癌，较为罕见，其演变模式因组织学和侵袭阶段的不同而有很大差异。治疗管理尚无明确界定，但正日益受到关注。这项回顾性单中心研究的描述性和分析性目标是分析TET患者的临床特征，并评估我们中心对这些肿瘤的管理情况。
方法
通过病理科筛选出2000年至2011年期间在雷恩大学医院接受治疗的成年TET患者。对他们的临床和病理特征以及生存情况进行回顾性分析。
结果
共检索到50例TET（46例胸腺瘤和4例胸腺癌）。其临床和组织学特征以及侵袭阶段与已发表的研究结果一致。其诊断和治疗管理也符合现行指南。单因素分析显示，重症肌无力和手术与较高的生存率相关。
结论
雷恩大学医院对TET的管理符合指南。
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