Mittal Mudit, Vashisth Pallavi, Chaubey K K, Dwivedi Swati, Arora Satyaki
J Tenn Dent Assoc. 2014 Spring-Summer;94(1):21-6; quiz 26-7.
Tetracycline hydrochloride has been shown to produce changes on periodontally involved root surfaces that can potentially enhance periodontal regeneration. This in vitro study was carried out to compare the root surface changes after scaling and root planing alone, and scaling and root planing followed by application of 100 mg/ml tetracycline hydrochloride under the Scanning Electron Microscope.
Fifteen periodontally compromised freshly extracted single-rooted teeth were thoroughly cleaned. The teeth were then sectioned into thirty blocks and divided into two groups. Group I (control) consisted of teeth which received scaling and and root planing alone and Group II received scaling and root planing followed by application of 100 mg/ml tetracycline hydrochloride under the Scanning Electron Microscope.
Tetracycline hydrochloride solution showed statistically highly significant removal of smear layer at 100 mg/ml solution (p < 0.001) and enlargement of dentinal tubule diameter (1.46 microm).
It can be concluded that tetracycline hydrochloride at concentration 100 mg/ml effectively removes the smear layer and enlarges the dentinal tubules.
盐酸四环素已被证明能使牙周受累的牙根表面产生变化,这可能会促进牙周组织再生。本体外研究旨在通过扫描电子显微镜比较单独进行龈下刮治和根面平整,以及龈下刮治和根面平整后应用100mg/ml盐酸四环素后的牙根表面变化。
15颗新鲜拔除的牙周受损单根牙被彻底清洁。然后将牙齿切成30个小块并分为两组。第一组(对照组)仅接受龈下刮治和根面平整,第二组在扫描电子显微镜下接受龈下刮治和根面平整,随后应用100mg/ml盐酸四环素。
盐酸四环素溶液在100mg/ml浓度时显示出统计学上极显著的玷污层去除效果(p < 0.001)以及牙本质小管直径增大(1.46微米)。
可以得出结论,100mg/ml浓度的盐酸四环素能有效去除玷污层并扩大牙本质小管。