Ho Edith Y, George Vijay, McCracken Marjorie, Ostroff James W
Division of Gastroenterology, Department of Medicine, Case Western Reserve University/Louis Stokes Cleveland Veterans Affairs Medical Center, Cleveland, OH, 44106, USA.
Department of Pathology and Laboratory Medicine, University of California San Francisco, CA, San Francisco, 94131, USA.
F1000Res. 2014 Apr 7;3:88. doi: 10.12688/f1000research.3252.1. eCollection 2014.
One well recognized and potentially serious complication of chronic immunosuppression in organ transplant recipients is post-transplantation lymphoproliferative disorders (PTLD). This accounts for 20% of all malignancies in transplant recipients, which is four times higher than the general population (1,2). The diagnosis of PTLD is often difficult, due to various manifestations resulting in late diagnosis. We report an unusual presentation of PTLD in a pediatric patient where the diagnosis was achieved only after extensive investigation.
器官移植受者慢性免疫抑制的一种公认且可能严重的并发症是移植后淋巴细胞增生性疾病（PTLD）。这占移植受者所有恶性肿瘤的20%，比普通人群高四倍（1,2）。由于各种表现导致诊断延迟，PTLD的诊断通常很困难。我们报告了一例儿科患者PTLD的不寻常表现，该患者仅在进行广泛检查后才得以确诊。
