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Lupiae 技术行杂交手术修复急性 A 型主动脉夹层:十年结果。

Hybrid repair of type A acute aortic dissections with the Lupiae technique: ten-year results.

机构信息

Department of Cardiac Surgery, Humanitas Gavazzeni Hospital, Bergamo, Italy.

Department of Cardiac Surgery, Humanitas Gavazzeni Hospital, Bergamo, Italy.

出版信息

J Thorac Cardiovasc Surg. 2015 Feb;149(2 Suppl):S99-104. doi: 10.1016/j.jtcvs.2014.07.099. Epub 2014 Aug 9.

Abstract

OBJECTIVES

Replacing the ascending aorta and the arch in patients with type A acute aortic dissection achieves good short-term results, but several patients are left with distal intimal tears or a patent false lumen in the descending aorta. In this series, we report the 10-year experience with the Lupiae technique, a hybrid aortic repair technique for patients with type A acute aortic dissection.

METHODS

From 2003 to 2013, 89 patients with type A acute aortic dissections underwent replacement of the ascending aorta, the arch, and the rerouting of the neck vessels on the ascending aorta, creating a proximal Dacron landing zone for a completion with thoracic endovascular aortic repair if necessary.

RESULTS

In-hospital mortality was 8.9%. In 16 patients, the false lumen healed spontaneously, whereas the remaining 65 patients underwent thoracic endovascular aortic repair. One patient died after thoracic endovascular aortic repair. Eighty patients were followed up. Complete thrombosis of the false lumen was obtained in 93.8% of patients. The median follow-up was 46 ± 35 months. Overall 8-year survival was 93.7% ± 5%, 100% for patients with spontaneously healed residual false lumen after just type A acute aortic dissection repair and 92.3% ± 7.7% for patients who underwent thoracic endovascular aortic repair after type A acute aortic dissection repair. In 10 years, 1 patient underwent a reoperation on the distal aorta (1.25%).

CONCLUSIONS

The availability of a Dacron landing zone on the distal ascending aorta after type A acute aortic dissection repair allows the exclusion, with a thoracic endovascular aortic repair, of any residual intimal tear refilling a patent false lumen. This approach seems to be associated with a high probability of false lumen thrombosis and low rates of reoperations on the distal aorta.

摘要

目的

在急性 A 型主动脉夹层患者中置换升主动脉和弓部可获得良好的短期效果,但部分患者的降主动脉仍存在远端内膜撕裂或假腔未闭。本系列报告了 Lupiae 技术治疗急性 A 型主动脉夹层患者的 10 年经验。

方法

2003 年至 2013 年,89 例急性 A 型主动脉夹层患者接受升主动脉、弓部置换和升主动脉颈血管转流术,在升主动脉上形成近端涤纶补片着陆区,以备必要时进行胸主动脉腔内修复术。

结果

院内死亡率为 8.9%。16 例患者的假腔自行愈合,其余 65 例患者接受了胸主动脉腔内修复术。1 例患者在胸主动脉腔内修复术后死亡。80 例患者得到随访。93.8%的患者假腔完全血栓形成。中位随访时间为 46±35 个月。总体 8 年生存率为 93.7%±5%,单纯急性 A 型主动脉夹层修复后假腔自行愈合的患者为 100%,急性 A 型主动脉夹层修复后行胸主动脉腔内修复术的患者为 92.3%±7.7%。10 年内,1 例患者再次接受远端主动脉手术(1.25%)。

结论

急性 A 型主动脉夹层修复术后升主动脉远端有涤纶补片着陆区,可通过胸主动脉腔内修复术排除任何残余内膜撕裂导致的假腔再通。这种方法似乎与假腔血栓形成的高概率和远端主动脉再手术率低相关。

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