Mehrotra T N, Bhatia R, Mehrotra R
Indian Heart J. 1989 Mar-Apr;41(2):105-7.
Twenty-six hypertensive patients and 25 control subjects were studied, and their systolic time intervals (STI) were measured. It was found that an alteration in STI, signifying left ventricular dysfunction, sets in most of the hypertensives earlier than any evidence of left ventricular hypertrophy (LVH) by clinical, radiological or electrocardiographic criteria. The parameters affected are the PEP interval which shows prolongation and PEP/LVET ratio which is increased. After treatment, the left ventricular performance was found to improve in those who did not reveal evidence of LVH. Thus, STI may be a sensitive indicator of early left ventricular dysfunction in hypertensives and a useful guide to assess improvement after treatment at a stage when other non-invasive methods are not so useful.
对26名高血压患者和25名对照受试者进行了研究，并测量了他们的收缩期时间间期（STI）。结果发现，STI的改变表明左心室功能障碍，在大多数高血压患者中比根据临床、放射学或心电图标准出现的任何左心室肥厚（LVH）证据更早出现。受影响的参数是显示延长的PEP间期和增加的PEP/LVET比值。治疗后，未显示LVH证据的患者左心室功能得到改善。因此，STI可能是高血压患者早期左心室功能障碍的敏感指标，并且在其他非侵入性方法不太有用的阶段，是评估治疗后改善情况的有用指南。
