成人烟雾病联合（直接/间接）血运重建的双功超声血流动力学研究。
Hemodynamic study with duplex ultrasonography on combined (direct/indirect) revascularization in adult moyamoya disease.
作者信息
Wang Yong, Chen Li, Wang Yida, Pan Huiwen, Wang Yi, Xu Bin, Liao Yujun
机构信息
Department of Ultrasound, Fudan University Affiliated Huashan Hospital Jing'An Branch, Shanghai, China.
Department of Neurosurgery, Fudan University Affiliated Huashan Hospital, Shanghai, China.
出版信息
J Stroke Cerebrovasc Dis. 2014 Nov-Dec;23(10):2573-2579. doi: 10.1016/j.jstrokecerebrovasdis.2014.05.024. Epub 2014 Sep 26.
BACKGROUND
To evaluate the hemodynamic changes by duplex ultrasonography in adult moyamoya disease (MMD) patients who underwent combined direct and indirect revascularization surgery.
METHODS
Seventeen adult patients underwent direct and indirect revascularization surgery in our hospital. Hemodynamic parameters, peak systolic velocity (PSV), end-diastolic velocity (EDV) and resistance index (RI), were determined by color Doppler at the baseline, 2 weeks, and 6 months after bypass.
RESULTS
Both the PSV and EDV of direct bypass were lower at 6 months after surgery compared with those at 2 weeks postoperatively. The EDV of indirect revascularization surgery of the maxillary artery (MA) at 6 months after surgery was higher and the RI of the MA lower compared with the baseline levels. Decreased PSV and EDV in the bypass vessel did not significantly correlate with increased EDV or decreased RI of the MA.
CONCLUSIONS
Duplex ultrasonography is a reliable, noninvasive tool to assess hemodynamic changes and evaluate the therapeutic performance of combined bypass surgery in adult MMD.
背景
通过双功超声评估接受直接和间接血管重建联合手术的成人烟雾病（MMD）患者的血流动力学变化。
方法
17例成年患者在我院接受直接和间接血管重建手术。通过彩色多普勒在搭桥术前、术后2周和6个月测定血流动力学参数，即收缩期峰值流速（PSV）、舒张末期流速（EDV）和阻力指数（RI）。
结果
与术后2周相比，直接搭桥术后6个月的PSV和EDV均降低。与基线水平相比，术后6个月上颌动脉（MA）间接血管重建手术的EDV升高，MA的RI降低。搭桥血管中PSV和EDV的降低与MA中EDV的升高或RI的降低无显著相关性。
结论
双功超声是评估血流动力学变化和评价成人MMD联合搭桥手术治疗效果可靠的无创工具。
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