与磷化铝中毒相关的严重可逆性心肌损伤：一例报告及文献综述
Severe reversible myocardial injury associated with aluminium phosphide toxicity: A case report and review of literature.
作者信息
Elabbassi Wael, Chowdhury Mohammed Andaleeb, Fachtartz Arif Al Nooryani
机构信息
Department of Cardiology, Al Qassimi Hospital, Sharjah.
Department of Internal Medicine, University of Toledo, OH.
出版信息
J Saudi Heart Assoc. 2014 Oct;26(4):216-21. doi: 10.1016/j.jsha.2013.11.006. Epub 2013 Dec 7.
Abstract
Aluminium phosphide is commonly used as an insecticide and can be toxic to humans at the cellular level by interfering with mitochondrial energy metabolism. We report on three cases of severe aluminium phosphide cardio-toxicity, resulting in severe decrease in both ventricular heart functions. The first case succumbed to intractable ventricular arrhythmias complicated by multi-organ failure before she died; while the other two cases required invasive hemodynamic support and eventually improved over the course of 10-14 days. We describe our experience and the challenges faced while managing one of them.
摘要
磷化铝通常用作杀虫剂，可在细胞水平上干扰线粒体能量代谢，从而对人体产生毒性。我们报告了3例严重的磷化铝心脏毒性病例，这导致心室心脏功能严重下降。第一例在死亡前死于顽固性室性心律失常并伴有多器官衰竭；而另外两例需要有创血流动力学支持，最终在10 - 14天内病情好转。我们描述了我们在处理其中一例时的经验和面临的挑战。
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