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[带蒂胸骨甲状肌瓣同期重建声带治疗声门型T1和T2期肿瘤术后嗓音质量评估]

[Estimation of quality of voice after removal of neoplasms T1 and T2 of glottis with simultaneous reconstruction of vocal fold with pedunculated sterno-thyroid muscle flap].

作者信息

Ratajczak Jan, Wójtowicz Piotr, Krzeski Antoni

机构信息

Klinika Otolaryngologii Wydziału Lekarsko-Dentystycznego Warszawskiego Uniwersytetu Medycznego, Kierownik: prof. dr hab. n. med. Antoni Krzeski, Warszawa, Polska.

Klinika Otolaryngologii Wydziału Lekarsko-Dentystycznego Warszawskiego Uniwersytetu Medycznego, Kierownik: prof. dr hab. n. med. Antoni Krzeski, Warszawa, Polska.

出版信息

Otolaryngol Pol. 2014 Sep-Oct;68(5):258-63. doi: 10.1016/j.otpol.2014.04.001. Epub 2014 Apr 18.

Abstract

INTRODUCTION

In recent years there has been an increasing number of cases of cancer, including cancer of the larynx. The choice of treatment should be primarily dictated by the complete elimination of cancer, but from the point of view of the patient, an important factor to keep in mind, is the quality of the voice that will be created at the end of the therapeutic process.

AIM

The aim of this study was to evaluate the voice quality of patients after partial surgery of the larynx with vocal fold reconstruction pedunculated sterno-thyroid muscle flap.

MATERIALS AND METHODS

The study included 30 men aged 53-72 years who were treated at the Clinic of Otorhinolaryngology Department of Medical-Dental Medical University of Warsaw on account of cancer of the larynx, qualified according to the TNM classification T1 or T2. The radical removal of cancer was associated with resection of one vocal fold, laryngeal pouches and ventricular fold. In 15 patients, included to the group I at the end of phase oncology surgery, a reconstruction of "vocal fold" pedunculated sterno-thyroid muscle flap were performed simultaneously. The group II consisted of 15 patients who underwent surgery that removed only the cancerous lesions. Impact assessments arising after surgery of voice disorders on quality of life were made using the self-test failure of the voice (Voice Handicap Index in the Pruszewicz modification). The nature of the created voice was studied using GRBAS scale. All patients performed the laryngostroboscope examination. With "IRIS" program, prepared by a team at Wrocław University of Technology, the voice was recorded, and then was subjected to acoustic analysis. In addition, noise level and the maximum phonation time was measured.

RESULTS

The results indicate that the patients of group I gained a better voice confirming the values of objective acoustic analysis. The assessment made by the scale GRBAS patients who supplemented the resulting loss after tumour removal, with much less hoarseness of voice, did not have the hyperkinesis and there was no puff character. They had the better flow of voice and phonation time of vowels "a" was much longer. The assessment of quality of life of patients in group I made in a test of the VHI was higher than in group II. The laryngostroboscope examination confirmed a good phonatory occlusion and a nearly regular, healthy vocal fold vibration in patients who had received flap of muscle.

CONCLUSIONS

Evaluation of the quality of voice after removing the tumor multiplicity in the glottis with simultaneous reconstruction "vocal fold" has confirmed that this is a very good surgical technique, which allows radically curing cancer for the simultaneous preservation of a good voice. The operation has limited indications for radiotherapy because of the desire to preserve the phonatory function of the larynx, and thus avoids the negative effects of radiation.

摘要

引言

近年来,包括喉癌在内的癌症病例数量不断增加。治疗方案的选择应首先以彻底清除癌症为导向,但从患者的角度来看,需要牢记的一个重要因素是治疗过程结束后所形成的嗓音质量。

目的

本研究的目的是评估采用带蒂胸骨甲状肌瓣进行声带重建的喉部分切除术后患者的嗓音质量。

材料与方法

该研究纳入了30名年龄在53至72岁之间的男性患者,他们因喉癌在华沙医科牙科大学耳鼻喉科诊所接受治疗,根据TNM分类为T1或T2期。癌症根治性切除包括切除一侧声带、喉囊和室带。在肿瘤外科手术阶段结束时,15名被纳入第一组的患者同时进行了带蒂胸骨甲状肌瓣“声带”重建术。第二组由15名仅接受癌性病变切除术的患者组成。使用嗓音自测失败(Pruszewicz改良版嗓音障碍指数)对嗓音障碍手术后对生活质量产生的影响进行评估。使用GRBAS量表研究所形成嗓音的性质。所有患者均接受了喉动态镜检查。使用弗罗茨瓦夫科技大学团队编写的“IRIS”程序对嗓音进行录音,然后进行声学分析。此外,还测量了噪音水平和最长发声时间。

结果

结果表明,第一组患者获得了更好的嗓音,这证实了客观声学分析的结果。GRBAS量表评估显示,在补充肿瘤切除后所造成的损失方面,第一组患者嗓音嘶哑程度轻得多,没有运动亢进,也没有气息声。他们的嗓音流畅性更好,元音“a”的发声时间长得多。在VHI测试中,第一组患者的生活质量评估高于第二组。喉动态镜检查证实,接受肌瓣移植的患者声门闭合良好,声带振动几乎正常、健康。

结论

对声门区多发肿瘤切除同时进行“声带”重建术后的嗓音质量评估证实,这是一种非常好的手术技术,可以在根治癌症的同时保留良好的嗓音。由于希望保留喉的发声功能,该手术放疗指征有限,从而避免了放疗的负面影响。

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