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终末期心力衰竭患者的外科治疗:机械支持与移植的比较。

Surgical treatments for patients with terminal heart failure: mechanical support compared with transplantation.

机构信息

Research Centre and Department of Cardiac Surgery, Montreal Heart Institute, Université de Montréal, Montreal, Québec, Canada.

Research Centre and Department of Cardiac Surgery, Montreal Heart Institute, Université de Montréal, Montreal, Québec, Canada.

出版信息

Can J Cardiol. 2014 Dec;30(12 Suppl):S455-8. doi: 10.1016/j.cjca.2014.06.024. Epub 2014 Jul 3.

Abstract

Heart transplantation remains the gold standard treatment for patients with terminal end-stage heart failure. Although results reported have been excellent, older recipients and donors associated with significant comorbidities are now the rule rather than the exception. Moreover, heart failure has become a significant public health problem with a growing population of patients in countries unable to answer the demand for transplantation. An emerging answer to this dilemma comes from results reported with the use of continuous flow pumps where patient survival approaches 80% one and 2 years after implantation in selected patients. Is it time to triage patients to continuous flow pumps? Should we recommend continuous flow pump implantations in patients with various comorbidities, and offer transplantation to a selected group of patients who will reach the long-term benefit of the procedure?

摘要

心脏移植仍然是终末期心力衰竭患者的金标准治疗方法。尽管报告的结果非常出色,但现在老年受者和伴有严重合并症的供者已成为常态,而非例外。此外,心力衰竭已成为一个重大的公共卫生问题,在一些国家,患者人数不断增加,但无法满足移植需求。连续流动泵的使用结果为这一困境提供了一个新的解决方案,在某些选定的患者中,使用连续流动泵移植后 1 年和 2 年的患者生存率接近 80%。现在是否到了对患者进行连续流动泵分类的时间?我们是否应该建议患有各种合并症的患者进行连续流动泵植入,并向将受益于该手术的选定患者提供移植?

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