一种主要组织相容性复合体II类基因转录调控的模型。
A model for the transcriptional regulation of MHC class II genes.
作者信息
Sullivan K E, Calman A F, Nakanishi M, Tsang S Y, Wang Y, Peterlin B M
机构信息
Howard Hughes Medical Institute and Department of Medicine and of Microbiology and Immunology, University of California, San Francisco, CA 94143, USA.
出版信息
Immunol Today. 1987;8(10):289-93. doi: 10.1016/0167-5699(87)90013-2.
The analysis of la antigens has focused primarily on their structure and function. However, the quantitative differences in immune response gene expression are equally important, since variation of cell surface la influences immunoregulation and the expression of immunologically mediated disease. Here, Kate Sullivan and her colleagues review the current knowledge of and propose a model for the transcriptional regulation of immune response gene expression.
对Ia抗原的分析主要集中在其结构和功能上。然而，免疫反应基因表达的定量差异同样重要，因为细胞表面Ia的变化会影响免疫调节以及免疫介导疾病的表达。在此，凯特·沙利文及其同事回顾了当前关于免疫反应基因表达转录调控的知识，并提出了一个模型。
Zotero 插件