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多发性内分泌腺瘤1型综合征与棕色脂肪瘤:一种罕见的关联?

MEN1 Syndrome and Hibernoma: An Uncommonly Recognised Association?

作者信息

Hedayati Venus, Thway Khin, Thomas J Meirion, Moskovic Eleanor

机构信息

Royal Marsden Hospital, Fulham Road, London SW3 6JJ, UK.

出版信息

Case Rep Med. 2014;2014:804580. doi: 10.1155/2014/804580. Epub 2014 Sep 22.

Abstract

MEN1 syndrome is known to classically result in parathyroid, pituitary, and pancreatic islet cell tumours. However, the potential association of MEN1 syndrome with hibernoma, a benign tumour with differentiation towards brown fat, is far less well known, despite their genetic profile both being linked to deletion of the MEN1 gene. Herein, we describe a case with its key radiological and pathological findings.

摘要

已知多发性内分泌腺瘤1型(MEN1)综合征典型地会导致甲状旁腺、垂体和胰岛细胞瘤。然而,MEN1综合征与冬眠瘤(一种向棕色脂肪分化的良性肿瘤)之间的潜在关联却鲜为人知,尽管它们的基因特征都与MEN1基因缺失有关。在此,我们描述一例具有关键影像学和病理学表现的病例。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/20b2/4189526/5765d62ad6f0/CRIM2014-804580.001.jpg

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